Circulating adiponectin as a biomarker in renal cell carcinoma: a systematic review and meta-analysis

被引：6

作者：

Yap, Ning Yi ^{[1
]}

Yap, Foo Ngan ^{[2
]}

Perumal, Komathi ^{[1
]}

Rajandram, Retnagowri ^{[1
]}

机构：

[1] Univ Malaya, Dept Surg, Fac Med, Kuala Lumpur 50605, Malaysia

[2] Univ Kuala Lumpur, Community Based Dept, Royal Coll Med Perak, Perak, Malaysia

来源：

BIOMARKERS | 2019年 / 24卷 / 06期

关键词：

Adiponectin; adipokine; circulating; obesity; renal cell carcinoma; CANCER-RISK; OBESITY; LEPTIN; LEVEL; SIZE;

D O I：

10.1080/1354750X.2019.1634763

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Context: Metabolic imbalance in renal cell carcinoma (RCC) can lead to abnormal adiponectin levels. Objective: To evaluate circulating adiponectin as a detection or predictive marker for RCC. Methods: A comprehensive literature search and meta-analysis was performed on studies reporting circulating adiponectin levels and RCC. The meta-analysis was performed using RevMan. Results: Seven studies compared the circulating adiponection levels between RCC cases and controls. Adiponectin level was significantly lower in RCC cases compared to controls at pre-diagnosis and pre-operative time-points. RCC stage, grade and subtype did not affect adiponectin levels. Conclusion: Low circulating adiponectin could be a predictive or risk factor for RCC.

引用

页码：607 / 614

页数：8

共 50 条

[21] Sarcomatoid component and the risk of renal cell carcinoma: a systematic review and meta-analysis
Liu, Xingchen
Qi, Ping
Jin, Jianbin
Svatek, Robert
Rodriguez, Ronald
Wang, Zhiping
Yin, Yongsheng
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 11 (06): : 5444 - 5456
[22] Renal cell carcinoma: a systematic review and meta-analysis on expression of androgen receptor
Abdi, Hossein
Mozaffari, Hamid Reza
Payandeh, Mehrdad
Sadeghi, Edris
BIOMEDICAL RESEARCH AND THERAPY, 2018, 5 (11): : 2820 - 2826
[23] Adiponectin and Sarcopenia: A Systematic Review With Meta-Analysis
Komici, Klara
Dello Iacono, Antonio
De Luca, Antonio
Perrotta, Fabio
Bencivenga, Leonardo
Rengo, Giuseppe
Rocca, Aldo
Guerra, Germano
FRONTIERS IN ENDOCRINOLOGY, 2021, 12
[24] Circulating adiponectin and carotid intima-media thickness: A systematic review and meta-analysis
Gasbarrino, Karina
Gorgui, Jessica
Nauche, Benedicte
Cote, Robert
Daskalopoulou, Stella S.
METABOLISM-CLINICAL AND EXPERIMENTAL, 2016, 65 (07): : 968 - 986
[25] Circulating Adiponectin Levels Are Paradoxically Associated With Mortality Rate: A Systematic Review and Meta-Analysis
Scarale, Maria Giovanna
Fontana, Andrea
Trischitta, Vincenzo
Copetti, Massimiliano
Menzaghi, Claudia
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2019, 104 (05): : 1357 - 1368
[26] Circulating VEGF as a biomarker for diagnosis of ovarian cancer: a systematic review and a meta-analysis
Liang, Bin
He, Qun
Zhong, Liansheng
Wang, Shaocheng
Pan, Zhongcheng
Wang, Tianjiao
Zhao, Yujie
ONCOTARGETS AND THERAPY, 2015, 8 : 1075 - 1082
[27] Systematic Review and STARD Scoring of Renal Cell Carcinoma Circulating Diagnostic Biomarker Manuscripts
Iafolla, Marco A. J.
Picardo, Sarah
Aung, Kyaw
Hansen, Aaron R.
JNCI CANCER SPECTRUM, 2020, 4 (05)
[28] Systematic review and REMARK scoring of renal cell carcinoma prognostic circulating biomarker manuscripts
Lafolla, Marco A. J.
Picardo, Sarah
Aung, Kyaw
Hansen, Aaron R.
PLOS ONE, 2019, 14 (10):
[29] Re: Genomics of Clear-Cell Renal Cell Carcinoma: A Systematic Review and Meta-Analysis
Bui, T. O.
Dao, V. T.
Nguyen, V. T.
Feugeas, J. -P.
Pamoukdjian, F.
Bousquet, G.
JOURNAL OF UROLOGY, 2022, 208 (03): : 732 - 733
[30] Systematic Review and Meta-Analysis: Circulating miRNAs for Diagnosis of Hepatocellular Carcinoma
Huang, Jing-Tao
Liu, Song-Mei
Ma, Haiqing
Yang, Ying
Zhang, Xuan
Sun, Huanhuan
Zhang, Xiaoyan
Xu, Jianqing
Wang, Jin
JOURNAL OF CELLULAR PHYSIOLOGY, 2016, 231 (02) : 328 - 335

← 1 2 3 4 5 →