Cytokine Storm

被引：2222
作者：
Fajgenbaum, David C. [1 ]
June, Carl H. [2 ,3 ]
机构：
[1] Univ Penn, Perelman Sch Med, Dept Med, Div Translat Med & Human Genet,Ctr Cytokine Storm, Philadelphia, PA 19104 USA
[2] Univ Penn, Perelman Sch Med, Ctr Cellular Immunotherapies, Philadelphia, PA 19104 USA
[3] Univ Penn, Perelman Sch Med, Parker Inst Canc Immunotherapy, Philadelphia, PA 19104 USA
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2020年 / 383卷 / 23期
关键词：
MACROPHAGE ACTIVATION SYNDROME; JUVENILE IDIOPATHIC ARTHRITIS; CD8(+) T-CELLS; RELEASE SYNDROME; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; INTERFERON-GAMMA; DISEASE; IMMUNE; INTERLEUKIN-18; BLINATUMOMAB;
D O I：
10.1056/NEJMra2026131
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Cytokine storm, a life-threatening disorder involving cytokine elevations and immune-cell hyperactivation, has various causes and is characterized by constitutional symptoms, systemic inflammation, and multiorgan dysfunction. Selective interventions can ameliorate the illness.
引用
收藏
页码：2255 / 2273
页数：19
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