Mg2+, K+, and the Ribosome

被引:85
|
作者
Nierhaus, Knud H. [1 ]
机构
[1] Charite, Inst Med Phys & Biophys, D-13353 Berlin, Germany
关键词
ESCHERICHIA-COLI; POTASSIUM-DEFICIENCY; MAMMALIAN RIBOSOMES; MAGNESIUM CONTENT; PROTEIN; RIBONUCLEOPROTEIN; INACTIVATION; PARTICLES; SUBUNIT; IONS;
D O I
10.1128/JB.02297-14
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Mg2+ and K+ are the prevalent di- and monovalent cations inside the cells in all three domains, playing a dominant role in structure and function of biological macromolecules. Ribosomes bind a substantial fraction of total Mg2+ and K+ cations. In this issue of the Journal of Bacteriology, Akanuma and coworkers (G. Akanuma et al., J. Bacteriol. 196:3820-3830, 2014, doi: 10.1128/JB.01896-14) report a surprising genetic link between ribosome amounts per cell and the intracellular Mg2+ concentrations.
引用
收藏
页码:3817 / 3819
页数:3
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