Vitamin D and breast cancer

被引：2

作者：

Nagykalnai Tamas ^{[1
]}

Landherr Laszlo ^{[2
]}

Nagy Andras Csaba ^{[3
]}

机构：

[1] Bajcsy Zsilinszky Korhaz, Ker Onkol Gondoz 17, Budapest, Hungary

[2] Uzsoki Utcai Korhaz, Fovarosi Onkoradiol Kozpont, Budapest, Hungary

[3] Uzsoki Utcai Korhaz, Budapest, Hungary

来源：

ORVOSI HETILAP | 2014年 / 155卷 / 28期

关键词：

breast cancer; serum vitamin D level; vitamin D supplementation; conflicting relationship; SERUM 25-HYDROXYVITAMIN D; D SUPPLEMENTATION; RISK; METAANALYSIS; SURVIVAL; OUTCOMES; HEALTH; WOMEN; TRIAL;

D O I：

10.1556/OH.2014.29906

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The active form of vitamin D, in conjunction with his own receptor, affect a multitude of biological processes in the cell (inter alia it influences the expression of oncogenes and tumor suppressor genes). There is an increasing volume of scientific publications examining the relationships between serum vitamin D levels, vitamin D supplementation and malignant diseases. Some articles suggest inverse relationship between the low serum levels of vitamin D and the breast cancer risk and mortality, whilst other publications do not support this view. Thus the present opinion is conflicted. Vitamin D can exert a beneficial influence on the symptoms and outcomes of a large number of ailments, but its role in affecting cancer is still not completely clear.

引用

页码：1091 / 1096

页数：6

共 33 条

[1] Serum vitamin D concentration and prostate cancer risk: A nested case-control study
Ahn, Jiyoung
Peters, Ulrike
Albanes, Demetrius
Purdue, Mark P.
Abnet, Christian C.
Chatterjee, Nilanjan
Horst, Ronald L.
Hollis, Bruce W.
Huang, Wen-Yi
Shikany, James M.
Hayes, Richard B.
[J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2008, 100 (11): : 796 - 804
[2] Plasma Vitamin D Levels, Menopause, and Risk of Breast Cancer Dose-Response Meta-Analysis of Prospective Studies
Bauer, Scott R.
Hankinson, Susan E.
Bertone-Johnson, Elizabeth R.
Ding, Eric L.
[J]. MEDICINE, 2013, 92 (03) : 123 - 131
[3] The effect of vitamin D supplementation on skeletal, vascular, or cancer outcomes: a trial sequential meta-analysis
Bolland, Mark J.
Grey, Andrew
Gamble, Greg D.
Reid, Ian R.
[J]. LANCET DIABETES & ENDOCRINOLOGY, 2014, 2 (04) : 307 - 320
[4] Prognostic Role of Vitamin D Status and Efficacy of Vitamin D Supplementation in Cancer Patients: A Systematic Review
Buttigliero, Consuelo
Monagheddu, Chiara
Petroni, Paola
Saini, Andrea
Dogliotti, Luigi
Ciccone, Giovannino
Berruti, Alfredo
[J]. ONCOLOGIST, 2011, 16 (09) : 1215 - 1227
[5] Vitamin D receptor signaling mechanisms: Integrated actions of a well-defined transcription factor
Carlberg, Carsten
Campbell, Moray J.
[J]. STEROIDS, 2013, 78 (02) : 127 - 136
[6] Calcium Plus Vitamin D Supplementation and Health Outcomes Five Years After Active Intervention Ended: The Women's Health Initiative
Cauley, Jane A.
Chlebowski, Rowan T.
Wactawski-Wende, Jean
Robbins, John A.
Rodabough, Rebecca J.
Chen, Zhao
Johnson, Karen C.
O'Sullivan, Mary Jo
Jackson, Rebecca D.
Manson, JoAnn E.
[J]. JOURNAL OF WOMENS HEALTH, 2013, 22 (11) : 915 - 929
[7] Clark A. S., 2012, CANC RES S3, V72
[8] Vitamin D, but not bone turnover markers, predict relapse in women with early breast cancer: an AZURE translational study.
Coleman, R. E.
Rathbone, E. J.
Marshall, H. C.
Wilson, C.
Brown, J. E.
Gossiel, F.
Gregory, W. M.
Cameron, D.
Bell, R.
[J]. CANCER RESEARCH, 2012, 72
[9] Vitamin D supplementation and response to aromatase inhibitors in postmenopausal women with hormone-receptor positive breast cancer
Dizdar, Omer
Bulut, Nilufer
Altundag, Kadri
[J]. BREAST, 2008, 17 (02) : 120 - 120
[10] Plasma 25-hydroxyvitamin D and risk of breast cancer in the Nurses' Health Study II
Eliassen, A. Heather
Spiegelman, Donna
Hollis, Bruce W.
Horst, Ronald L.
Willett, Walter C.
Hankinson, Susan E.
[J]. BREAST CANCER RESEARCH, 2011, 13 (03)

← 1 2 3 4 →