Hungarian adaptation and launch of the 2019 ARIA care pathways of allergic rhinitis in Hungary

被引：1

作者：

Helga, Kraxner ^{[1
]}

Andor, Hirschberg ^{[2
]}

Kristof, Nekam ^{[2
]}

机构：

[1] Semmelweis Egyet, Ful Orr Gegeszeti Fej Nyaksebeszeti Klin, Altalanos Orvostudomanyi Kar, Budapest, Hungary

[2] Ful Orr Gegeszeti Fej Nyaksebeszeti Klin, Uj Szent Janos Korhaz Szakrendelo, Eszak Kozepbudai Ctr, Budapest, Hungary

来源：

ORVOSI HETILAP | 2020年 / 161卷 / 49期

关键词：

allergic rhinitis; allergen-specific immunotherapy; integrative care pathways; real-world evidence; MASK algorithm; EAACI AIT GUIDELINES; SUBLINGUAL IMMUNOTHERAPY; FLUTICASONE FUROATE; NASAL SPRAY; ASTHMA; IMPACT; QUALITY; ONSET; RECOMMENDATIONS; IMPLEMENTATION;

D O I：

10.1556/650.2020.31919

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The number of allergic patients is increasing all over the world, also in Hungary. Delivering effective and cost-effective health care is essential for all health care systems. ARIA (Allergic Rhinitis and its Impact on Asthma) aims to improve the care of patients who suffer from allergic rhinitis by setting up guidelines and updating them. Development of ICPs (integrated care pathways) can play an essential role in attaining this goal. Our aim is to make ICP-s developed by ARIA available also in Hungary, as is already the case in other countries of the European Union (EU). Together with other international initiatives, ARIA has worked out digitally-enabled ICPs to support care in allergic rhinitis and comorbid asthma. ICPs are based on new-generation guidelines using RWE (real-world evidence) from chamber studies and mobile technology. The MASK (Mobile Airways Sentinel NetworK) algorithm - based on visual analogue scale - was digitalized to support pharmacotherapy, and was refined by using RWE. ARIA was the first to develop ICPs for allergen immunotherapy (AIT) in 2019. Based on MASK data, patients did not follow guidelines and their adherence to treatment was poor. Patients would modify their treatments, depending on the disease control. The effect of fluticasone propionate-azelastine combination is superior to intranasal corticosteroids which are superior to oral H-1-antihistamines. Electronic diaries obtained from cell phones and other 'mobile health' (mHealth) devices help select patients for AIT. The ARIA algorithm for AR was found appropriate and no change is necessary. These guidelines will inform ICPs and will be included in the DG Sante digitally-enabled, person-centred care system. AIT is an effective treatment for allergic diseases caused by inhaled allergens. Its use should, however, be restricted to carefully selected patients.

引用

页码：2059 / 2071

页数：13

共 70 条

[1]

[Anonymous], SUMM PROD CHAR AC 12

[2]

[Anonymous], 2008, EMEACHMPBWP304831200

[3] Rapid onset of action and reduced nasal hyperreactivity: new targets in allergic rhinitis management [J].

Bachert, C. ;

Bousquet, J. ;

Hellings, P. .

CLINICAL AND TRANSLATIONAL ALLERGY, 2018, 8

[4] Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study [J].

Bedard, Annabelle ;

Basagana, Xavier ;

Anto, Josep M. ;

Garcia-Aymerich, Judith ;

Devillier, Philippe ;

Arnavielhe, Sylvie ;

Bedbrook, Anna ;

Onorato, Gabrielle L. ;

Czarlewski, Wienczyslawa ;

Murray, Ruth ;

Almeida, Rute ;

Fonseca, Joao ;

Costa, Elisio ;

Malva, Joao ;

Morais-Almeida, Mario ;

Pereira, Ana Margarida ;

Todo-Bom, Ana ;

Menditto, Enrica ;

Stellato, Cristiana ;

Ventura, Maria Teresa ;

Cruz, Alvaro A. ;

Stelmach, Rafael ;

da Silva, Jane ;

Larenas-Linnemann, Desiree ;

Fuentes-Perez, Jose M. ;

Huerta-Villalobos, Yunuen R. ;

Emuzyte, Regina ;

Kvedariene, Violeta ;

Valiulis, Arunas ;

Kuna, Piotr ;

Samolinski, Boleslaw ;

Klimek, Ludger ;

Mosges, Ralph ;

Pfaar, Oliver ;

Shamai, Sara ;

Annesi-Maesano, Isabelle ;

Bosse, Isabelle ;

Demoly, Pascal ;

Fontaine, Jean-Francois ;

Cardona, Vicky ;

Mullol, Joaquim ;

Valero, Antonio ;

Roller-Wirnsberger, Regina E. ;

Tomazic, Peter Valentin ;

Chavannes, Niels H. ;

Fokkens, Wytske J. ;

Reitsma, Sietze ;

Bewick, Mike ;

Ryan, Dermot ;

Sheikh, Aziz .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2019, 144 (01) :135-+

[5] Solving the Problem of Nonadherence to Immunotherapy [J].

Bender, Bruce G. ;

Lockey, Richard F. .

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA, 2016, 36 (01) :205-+

[6] Allergen manufacturing and quality aspects for allergen immunotherapy in Europe and the United States: An analysis from the EAACI AIT Guidelines Project [J].

Bonertz, A. ;

Roberts, G. ;

Slater, J. E. ;

Bridgewater, J. ;

Rabin, R. L. ;

Hoefnagel, M. ;

Timon, M. ;

Pini, C. ;

Pfaar, O. ;

Sheikh, A. ;

Ryan, D. ;

Akdis, C. ;

Goldstein, J. ;

Poulsen, L. K. ;

van Ree, R. ;

Rhyner, C. ;

Barber, D. ;

Palomares, O. ;

Pawankar, R. ;

Hamerlijnk, D. ;

Klimek, L. ;

Agache, I. ;

Angier, E. ;

Casale, T. ;

Fernandez-Rivas, M. ;

Halken, S. ;

Jutel, M. ;

Lau, S. ;

Pajno, G. ;

Sturm, G. ;

Varga, E. M. ;

van Wijk, R. Gerth ;

Bonini, S. ;

Muraro, A. ;

Vieths, S. .

ALLERGY, 2018, 73 (04) :816-826

[7] Challenges in the implementation of EAACI guidelines on allergen immunotherapy: A global perspective on the regulation of allergen products [J].

Bonertz, A. ;

Roberts, G. C. ;

Hoefnagel, M. ;

Timon, M. ;

Slater, J. E. ;

Rabin, R. L. ;

Bridgewater, J. ;

Pini, C. ;

Pfaar, O. ;

Akdis, C. ;

Goldstein, J. ;

Poulsen, L. K. ;

van Ree, R. ;

Rhyner, C. ;

Barber, D. ;

Palomares, O. ;

Sheikh, A. ;

Pawankar, R. ;

Hamerlijnk, D. ;

Klimek, L. ;

Agache, I. ;

Angier, E. ;

Casale, T. ;

Fernandez-Rivas, M. ;

Halken, S. ;

Jutel, M. ;

Lau, S. ;

Pajno, G. ;

Sturm, G. ;

Varga, E. M. ;

van Wijk, R. Gerth ;

Bonini, S. ;

Muraro, A. ;

Vieths, S. .

ALLERGY, 2018, 73 (01) :64-76

[8] ARIA pharmacy 2018 "Allergic rhinitis care pathways for community pharmacy" AIRWAYS ICPs initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Sante) \nPOLLAR (Impact of Air POLLution on Asthma and Rhinitis)\nGARD Demonstration project [J].

Bosnic-Anticevich, Sinthia ;

Costa, Elisio ;

Menditto, Enrica ;

Lourenco, Olga ;

Novellino, Ettore ;

Bialek, Slawomir ;

Briedis, Vitalis ;

Buonaiuto, Roland ;

Chrystyn, Henry ;

Cvetkovski, Biljana ;

Di Capua, Stefania ;

Kritikos, Vicky ;

Mair, Alpana ;

Orlando, Valentina ;

Paulino, Ema ;

Salimaki, Johanna ;

Soderlund, Rojin ;

Tan, Rachel ;

Williams, Dennis M. ;

Wroczynski, Piotr ;

Agache, Ioana ;

Ansotegui, Ignacio J. ;

Anto, Josep M. ;

Bedbrook, Anna ;

Bachert, Claus ;

Bewick, Mike ;

Bindslev-Jensen, Carsten ;

Brozek, Jan L. ;

Canonica, Giorgio Walter ;

Cardona, Victoria ;

Carr, Warner ;

Casale, Thomas B. ;

Chavannes, Niels H. ;

de Sousa, Jaime Correia ;

Cruz, Alvaro A. ;

Czarlewski, Wienczyslawa ;

De Carlo, Giuseppe ;

Demoly, Pascal ;

Devillier, Philippe ;

Dykewicz, Mark S. ;

Gaga, Mina ;

El-Gamal, Yehia ;

Fonseca, Joao ;

Fokkens, Wytske J. ;

Antonieta Guzman, Maria ;

Haahtela, Tari ;

Hellings, Peter W. ;

Illario, Maddalena ;

Carlos Ivancevich, Juan ;

Just, Jocelyne .

ALLERGY, 2019, 74 (07) :1219-1236

[9] Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen) [J].

Bousquet, J. ;

Khaltaev, N. ;

Cruz, A. A. ;

Denburg, J. ;

Fokkens, W. J. ;

Togias, A. ;

Zuberbier, T. ;

Baena-Cagnani, C. E. ;

Canonica, G. W. ;

van Weel, C. ;

Agache, I. ;

Ait-Khaled, N. ;

Bachert, C. ;

Blaiss, M. S. ;

Bonini, S. ;

Boulet, L. -P. ;

Bousquet, P. -J. ;

Camargos, P. ;

Carlsen, K. -H. ;

Chen, Y. ;

Custovic, A. ;

Dahl, R. ;

Demoly, P. ;

Douagui, H. ;

Durham, S. R. ;

van Wijk, R. Gerth ;

Kalayci, O. ;

Kaliner, M. A. ;

Kim, Y. -Y. ;

Kowalski, M. L. ;

Kuna, P. ;

Le, L. T. T. ;

Lemiere, C. ;

Li, J. ;

Lockey, R. F. ;

Mavale-Manuel, S. ;

Meltzer, E. O. ;

Mohammad, Y. ;

Mullol, J. ;

Naclerio, R. ;

Hehir, R. E. O. ;

Ohta, K. ;

Ouedraogo, S. ;

Palkonen, S. ;

Papadopoulos, N. ;

Passalacqua, G. ;

Pawankar, R. ;

Popov, T. A. ;

Rabe, K. F. ;

Rosado-Pinto, J. .

ALLERGY, 2008, 63 :8-+

[10] Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma [J].

Bousquet, J. ;

Bedbrook, A. ;

Czarlewski, W. ;

Onorato, G. L. ;

Arnavielhe, S. ;

Laune, D. ;

Mathieu-Dupas, E. ;

Fonseca, J. ;

Costa, E. ;

Lourenco, O. ;

Morais-Almeida, M. ;

Todo-Bom, A. ;

Illario, M. ;

Menditto, E. ;

Canonica, G. W. ;

Cecchi, L. ;

Monti, R. ;

Napoli, L. ;

Ventura, M. T. ;

De Feo, G. ;

Fokkens, W. J. ;

Chavannes, N. H. ;

Reitsma, S. ;

Cruz, A. A. ;

da Silva, J. ;

Serpa, F. S. ;

Larenas-Linnemann, D. ;

Perez, J. M. Fuentes ;

Huerta-Villalobos, Y. R. ;

Rivero-Yeverino, D. ;

Rodriguez-Zagal, E. ;

Valiulis, A. ;

Dubakiene, R. ;

Emuzyte, R. ;

Kvedariene, V. ;

Annesi-Maesano, I. ;

Blain, H. ;

Bonniaud, P. ;

Bosse, I. ;

Dauvilliers, Y. ;

Devillier, P. ;

Fontaine, J. F. ;

Pepin, J. L. ;

Pham-Thi, N. ;

Portejoie, F. ;

Picard, R. ;

Roche, N. ;

Rolland, C. ;

Schmidt-Grendelmeier, P. ;

Kuna, P. .

CLINICAL AND TRANSLATIONAL ALLERGY, 2019, 9

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