Long-term recording from the chorda tympani nerve in rats

被引:12
作者
Shimatani, Y
Grabauskiene, S
Bradley, RM
机构
[1] Univ Michigan, Sch Dent, Dept Biol & Mat Sci, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Sch Med, Dept Physiol, Ann Arbor, MI 48109 USA
关键词
taste; chorda tympani nerve; chronic recording; rat;
D O I
10.1016/S0031-9384(02)00684-4
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Cuff electrodes with headcap connectors were implanted around the rat chorda tympani nerve. Whole nerve recordings under anesthesia were made from these nerves every week to chemical, thermal and tactile stimuli applied to the anterior tongue. The signal/noise ratio of these recordings was similar to acute recordings from the chorda tympani nerve, and the nerves were spontaneously active. Responses to chemical as well as thermal and mechanical stimulation of the tongue were recorded as early as 2 and 3 weeks after implantation and recordings from the same nerve were made for more than 3 months. These results have demonstrated the feasibility of making long-term chronic recordings of chemosensory activity in the chorda tympani nerve. The cuff electrode has great potential to provide correlative information between neurophysiological and behavioral data. (C) 2002 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:143 / 149
页数:7
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