Role of imunohistochemistry in the diagnosis of ocular lesions in mucocutaneous leishmaniasis. Report of five cases

被引：0

作者：

Nossa Moitinho, Livia Maria ^{[1
]}

Rodrigues de Freitas, Luiz Antonio ^{[2
,3
]}

Marback, Eduardo Ferrari ^{[2
,4
]}

Marback, Roberto Lorens ^{[2
,4
]}

机构：

[1] FBDC, Salvador, BA, Brazil

[2] Univ Fed Bahia, Salvador, BA, Brazil

[3] Fundacao Oswaldo Cruz, Salvador, BA, Brazil

[4] Univ Hosp, Salvador, BA, Brazil

来源：

REVISTA BRASILEIRA DE OFTALMOLOGIA | 2009年 / 68卷 / 03期

关键词：

Leishmaniasis/pathology; Eye infections; parasitic/diagnosis; Eye diseases/microbiology; Immunohistochemistry; Case reports; CUTANEOUS LEISHMANIASIS;

D O I：

10.1590/S0034-72802009000300006

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To describe the clinical, histopathological and immunoistochemical findings of ocular leishmaniasis in five patients presenting positive Montenegro reaction. Methods: Retrospective study in four years of the clinical charts, histopathologic and immunoistochemic study of the material obtained by biopsy of ocular lesions in five patients with positive Montenegro reaction. Results: The most frequent clinical findings was conjunctival hyperemia (2/5), followed by crusting lid lesion (1/5), conjunctival leukoplakia (1/5) and ocular itching (1/5). The histopathological study disclosed chronic inflammation (3/5) and pseudoepitheliomatous hyperplasia (2/5). The all patients that presented pseudoepitheliomatous hyperplasia in the biopsy material also presented immunohistochemical positivity for polyclonal antibody anti-leishmania. Conclusion: The immunoistochemical study was contribuitory for the diagnosis of ocular leishmaniasis in the five patients of this study.

引用

页码：152 / 155

页数：4

共 14 条

[1]

Amato Valdir S., 1998, Revista do Instituto de Medicina Tropical de Sao Paulo, V40, P23, DOI 10.1590/S0036-46651998000100006

[2]

AMATO VS, 1997, THESIS U SAO PAULO

[3] Chronic dacryocystitis in American mucocutaneous leishmaniasis [J].