CANCER EPIGENETICS Reading the future of leukaemia

被引:9
作者
Wilkinson, Alex W. [1 ]
Gozani, Or [1 ]
机构
[1] Stanford Univ, Dept Biol, Stanford, CA 94305 USA
关键词
MLL-REARRANGED LEUKEMIA; ELONGATION COMPLEX SEC; HOX GENE-EXPRESSION; RNA-POLYMERASE-II; AF9 YEATS DOMAIN; H3K79; METHYLATION; DOT1L; TRANSCRIPTION;
D O I
10.1038/nature21894
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The identification of the regulatory protein ENL as essential to an aggressive form of leukaemia provides insight into transcriptional regulation and highlights potential avenues for therapy. See Letters p.265 & p.270
引用
收藏
页码:186 / 188
页数:4
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