EXPERIMENTAL AND MOLECULAR MEDICINE
|
1996年
/
28卷
/
03期
关键词:
DNA-binding proteins;
dystrophin;
promoter;
D O I:
10.1038/emm.1996.20
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
The expression of dystrophin gene has been found to be regulated through different promoters in different tissues. To understand the mechanism of tissue specific selection of promoter DNA-protein interaction studies were carried out using tissue specific nuclear extracts. Several tissue specific binding proteins have been detected which could have their role in selection and maintenance of tissue specificity of promoters.