An evidence of presence of DNA-binding proteins in selection of dystrophin gene promoter

被引：0
作者：
Mishra, S [1 ]
Mittal, B [1 ]
机构：
[1] SANJAY GANDHI POSTGRAD INST MED SCI,DEPT GENET,MOL MYOPATHY LAB,LUCKNOW,UTTAR PRADESH,INDIA
来源：
EXPERIMENTAL AND MOLECULAR MEDICINE | 1996年 / 28卷 / 03期
关键词：
DNA-binding proteins; dystrophin; promoter;
D O I：
10.1038/emm.1996.20
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The expression of dystrophin gene has been found to be regulated through different promoters in different tissues. To understand the mechanism of tissue specific selection of promoter DNA-protein interaction studies were carried out using tissue specific nuclear extracts. Several tissue specific binding proteins have been detected which could have their role in selection and maintenance of tissue specificity of promoters.
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收藏
页码：131 / 134
页数：4
相关论文
共 15 条
  • [1] HUMAN AND MURINE DYSTROPHIN MESSENGER-RNA TRANSCRIPTS ARE DIFFERENTIALLY EXPRESSED DURING SKELETAL-MUSCLE, HEART, AND BRAIN-DEVELOPMENT
    BIES, RD
    PHELPS, SF
    CORTEZ, MD
    ROBERTS, R
    CASKEY, CT
    CHAMBERLAIN, JS
    [J]. NUCLEIC ACIDS RESEARCH, 1992, 20 (07) : 1725 - 1731
  • [2] BOYCE F, 1990, P NATL ACAD SCI USA, V88, P1276
  • [3] BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3
  • [4] DYSTROPHIN GENE TRANSCRIBED FROM DIFFERENT PROMOTERS IN NEURONAL AND GLIAL-CELLS
    CHELLY, J
    HAMARD, G
    KOULAKOFF, A
    KAPLAN, JC
    KAHN, A
    BERWALDNETTER, Y
    [J]. NATURE, 1990, 344 (6261) : 64 - 65
  • [5] TRANSCRIPTION OF THE DYSTROPHIN GENE IN HUMAN-MUSCLE AND NON-MUSCLE TISSUES
    CHELLY, J
    KAPLAN, JC
    MAIRE, P
    GAUTRON, S
    KAHN, A
    [J]. NATURE, 1988, 333 (6176) : 858 - 860
  • [6] GARABEDIAN MJ, 1992, GENE TRANSCRIPTION P, P244
  • [7] GILGENKRANTZ H, 1992, J BIOL CHEM, V267, P10823
  • [8] GORSKI K, 1986, CELL, V47, P787
  • [9] MOLECULAR AND FUNCTIONAL-ANALYSIS OF THE MUSCLE-SPECIFIC PROMOTER REGION OF THE DUCHENNE MUSCULAR-DYSTROPHY GENE
    KLAMUT, HJ
    GANGOPADHYAY, SB
    WORTON, RG
    RAY, PN
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (01) : 193 - 205
  • [10] MUNTONI F, 1995, AM J HUM GENET, V56, P151
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