Banking Stem Cells from Human Exfoliated Deciduous Teeth (SHED): Saving for the Future

被引:103
作者
Arora, Vipin [1 ]
Arora, Pooja [2 ]
Munshi, A. K. [3 ]
机构
[1] KD Dent Coll & Hosp, Dept Conservat Dent & Endodont, Mathura, India
[2] KD Dent Coll & Hosp, Dept Oral & Maxillofacial Prosthodont & Dent Impl, Mathura, India
[3] KD Dent Coll & Hosp, Dept Pediat Dent, Mathura, India
关键词
deciduous teeth; SHED; banking; HUMAN DENTAL-PULP; CRYOPRESERVATION; DEFECTS; REPAIR; SIZE;
D O I
10.17796/jcpd.33.4.y887672r0j703654
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Tooth derived cells are readily accessible and provide an easy and minimally invasive way to obtain and store stem cells for future use. Banking ones own tooth-derived stem cells is a reasonable and simple alternative to harvesting stem cells from other tissues. Obtaining stem cells from human exfoliated deciduous teeth (SHED) is simple and convenient, with little or no trauma. Every child loses primary teeth, which creates the perfect opportunity to recover and store this convenient source of stem cells - should they be needed to treat future injuries or ailments and presents a far better alternative to simply discarding the teeth or storing then? as mementos from the past. Furthermore, using ones own stem cells poses few, if any, risks for developing immune reactions or rejection following transplantation and also eliminates the potential of contracting disease from donor cells. Stem cells can also be recovered from developing wisdom teeth and permanent teeth. Individuals have different opportunities at different stages of their life to bank these valuable cells. It is best to recover stem cells when a child is young and healthy and the cells are strong and proliferative. The purpose of this review is to discuss the present scenario as well as the technical details of tooth banking as related to SHED cells.
引用
收藏
页码:289 / 294
页数:6
相关论文
共 22 条
  • [1] ABBAS DI, 2008, 96 PEF IADR
  • [2] Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cues
    Arthur, Agnes
    Rychkov, Grigori
    Shi, Songtao
    Koblar, Simon Andrea
    Gronthos, Stan
    [J]. STEM CELLS, 2008, 26 (07) : 1787 - 1795
  • [3] Dental pulp tissue engineering with stem cells from exfoliated deciduous teeth
    Cordeiro, Mabel M.
    Dong, Zhibong
    Kaneko, Tomoatsu
    Zhang, Zbaocbeng
    Miyazawa, Marta
    Sbl, Songtao
    Smitb, Antbony J.
    Noer, Jacques E.
    [J]. JOURNAL OF ENDODONTICS, 2008, 34 (08) : 962 - 969
  • [4] Costa AD, 2008, J CRANIOFAC SURG, V19, P204, DOI 10.1097/scs.0b013e31815c8a54
  • [5] Human dental pulp stem cells improve left ventricular function, induce angiogenesis, and reduce infarct size in rats with acute myocardial infarction
    Gandia, Carolina
    Arminan, Ana
    Garcia-Verdugo, Jose Manuel
    Lledo, Elisa
    Ruiz, Amparo
    Minana, M. Dolores
    Sanchez-Torrijos, Jorge
    Paya, Rafael
    Mirabet, Vicente
    Carbonell-Uberos, Francisco
    Llop, Mauro
    Montero, Jose Anastasio
    Sepulveda, Pilar
    [J]. STEM CELLS, 2008, 26 (03) : 638 - 645
  • [6] IAN RF, 2007, CHAPTER, V8, P187
  • [7] JEREMY J, 2008, NEW YORK STATE DENT, V74, P21
  • [8] Early transplantation of human immature dental pulp stem cells from baby teeth to golden retriever muscular dystrophy (GRMD) dogs: Local or systemic?
    Kerkis, Irina
    Ambrosio, Carlos E.
    Kerkis, Alexandre
    Martins, Daniele S.
    Zucconi, Eder
    Fonseca, Simone A. S.
    Cabral, Rosa M.
    Maranduba, Carlos M. C.
    Gaiad, Thais P.
    Morini, Adriana C.
    Vieira, Natassia M.
    Brolio, Marina P.
    Sant'Anna, Osvaldo A.
    Miglino, Maria A.
    Zatz, Mayana
    [J]. JOURNAL OF TRANSLATIONAL MEDICINE, 2008, 6 (1)
  • [9] Craniofacial tissue engineering by stem cells
    Mao, J. J.
    Giannobile, W. V.
    Helms, J. A.
    Hollister, S. J.
    Krebsbach, P. H.
    Longaker, M. T.
    Shi, S.
    [J]. JOURNAL OF DENTAL RESEARCH, 2006, 85 (11) : 966 - 979
  • [10] SHED: Stem cells from human exfoliated deciduous teeth
    Miura, M
    Gronthos, S
    Zhao, MR
    Lu, B
    Fisher, LW
    Robey, PG
    Shi, ST
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (10) : 5807 - 5812