Infrared and skin: Friend or foe

被引:146
作者
Barolet, Daniel [1 ,2 ]
Christiaens, Francois
Hamblin, Michael R. [3 ,4 ,5 ]
机构
[1] McGill Univ, Dept Med, Div Dermatol, Montreal, PQ H3A 1A1, Canada
[2] RoseLab Skin Opt Lab, Laval, PQ H7T 0G3, Canada
[3] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
[4] Harvard Univ, Sch Med, Dept Dermatol, Boston, MA 02115 USA
[5] Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA
关键词
Infrared (IR); IR-A; Photobiomodulation; MMP-1; Photoprevention; Irradiance; HUMAN DERMAL FIBROBLASTS; BIPHASIC DOSE-RESPONSE; LEVEL LIGHT THERAPY; PHOTODYNAMIC THERAPY; CELLULAR-RESPONSE; SUN PROTECTION; HAIRLESS MICE; EXPOSURE TIME; SHADOW RULE; IN-VIVO;
D O I
10.1016/j.jphotobiol.2015.12.014
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In the last decade, it has been proposed that the sun's IR-A wavelengths might be deleterious to human skin and that sunscreens, in addition to their desired effect to protect against UV-B and UV-A, should also protect against IR-A (and perhaps even visible light). Several studies showed that NIR may damage skin collagen content via an increase in MMP-1 activity in the same manner as is known for UVR. Unfortunately, the artificial NIR light sources used in such studies were not representative of the solar irradiance. Yet, little has been said about the other side of the coin. This article will focus on key information suggesting that IR-A may be more beneficial than deleterious when the skin is exposed to the appropriate irradiance/dose of IR-A radiation similar to daily sun exposure received by people in real life. IR-A might even precondition the skin a process called photoprevention from an evolutionary standpoint since exposure to early morning IR-A wavelengths in sunlight may ready the skin for the coming mid-day deleterious UVR. Consequently IR-A appears to be the solution, not the problem. It does more good than bad for the skin. It is essentially a question of intensity and how we can learn from the sun. (C) 2016 The Authors. Published by Elsevier B.V.
引用
收藏
页码:78 / 85
页数:8
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