Bacterial protein secretion - a target for new antibiotics?

被引：27

作者：

Stephens, C ^{[1
]}

Shapiro, L ^{[1
]}

机构：

[1] STANFORD UNIV, BECKMAN CTR MOL & GENET MED, DEPT DEV BIOL, STANFORD, CA 94305 USA

来源：

CHEMISTRY & BIOLOGY | 1997年 / 4卷 / 09期

关键词：

D O I：

10.1016/S1074-5521(97)90217-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The heavy use of antibiotics over recent decades has resulted in widespread resistance of bacteria to many drugs. Overcoming resistance requires new approaches to antibiotic development, including the exploitation of new targets in the bacterial cell. Protein secretion is essential for bacterial cell growth and virulence, so it could be a suitable target for new therapeutic agents.

引用

页码：637 / 641

页数：5

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