1,3,4-oxadiazole formation as traceless release in solid phase organic synthesis

被引：27

作者：

Cesarini, Sara ^{[1
]}

Colombo, Nicoletta ^{[1
]}

Pulici, Maurizio ^{[1
]}

Felder, Eduard R. ^{[1
]}

Brill, Wolfgang K. -D. ^{[1
]}

机构：

[1] Nerviano Med Sci, Dept Chem, I-20014 Nerviano, MI, Italy

来源：

TETRAHEDRON | 2006年 / 62卷 / 43期

关键词：

cyclative released traceless linker; dehydration; TFAA; transacylation;

D O I：

10.1016/j.tet.2006.08.016

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxadiazoles were generated upon a dehydrative cyclization reaction with 2-acyl hydrazides bound to the polymeric support via one of their N atoms using TFAA as a dehydration agent. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：10223 / 10236

页数：14

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