Responsive brain stimulation in epilepsy

被引:20
作者
Hartshorn, Alendia [1 ]
Jobst, Barbara [2 ]
机构
[1] Dartmouth Hitchcock Med Ctr, One Med Ctr Dr, Lebanon, NH 03756 USA
[2] Geisel Sch Med Dartmouth, Hanover, NH USA
关键词
deep brain stimulation; epilepsy; nerve stimulation; responsive neurostimulation; seizures; VAGUS NERVE-STIMULATION; TEMPORAL-LOBE EPILEPSY; PARTIAL-ONSET EPILEPSY; REFRACTORY EPILEPSY; CORTICAL STIMULATION; FOCAL EPILEPSY; THALAMIC-STIMULATION; ICTAL TACHYCARDIA; NEUROSTIMULATION; SEIZURES;
D O I
10.1177/2040622318774173
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Stimulation devices are considered in patients with drug-resistant epilepsy and who are not surgical candidates. Responsive neurostimulation (RNS) is a cortically based stimulator activated by electrocorticography (ECoG) patterns. Stimulation is applied directly to the seizure focus. The vagal nerve stimulator AspireSR 106 is also a responsive device which, in addition to basal stimulation, is activated by tachycardia. Deep brain stimulation of the anterior nucleus of the thalamus is used in Europe for intractable epilepsy and yields similar response rates to RNS using duty cycle stimulation. Chronic subthreshold cortical stimulation is an experimental form of constant, low-level stimulation applied to a seizure focus. These modalities are discussed and compared in this review.
引用
收藏
页码:135 / 142
页数:8
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