Accidental sulfur mustard exposure: A case report

被引:6
作者
Schmidt, Annette [1 ,2 ]
Steinritz, Dirk [1 ,3 ]
Rudolf, Klaus-Dieter [4 ]
Thiermann, Horst [1 ]
Striepling, Enno [4 ]
机构
[1] Bundeswehr Inst Pharmacol & Toxicol, Neuherbergstr 11, D-803397 Munich, Germany
[2] Bundeswehr Univ Munich, Fac Human Sci, Werner Heisenberg Weg 39, D-85577 Neubiberg, Germany
[3] Ludwig Maximilians Univ Munchen, Walther Straub Inst Pharmacol & Toxicol, D-80336 Munich, Germany
[4] BG Hosp Hamburg, Dept Hand Surg Plast & Microsurg, Burn Ctr, Bergedorfer Str 10, D-21033 Hamburg, Germany
关键词
Sulfur mustard; Exposure; Accident; Excision; Split-skin grafting; SKIN;
D O I
10.1016/j.toxlet.2017.11.023
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
The clinical progression following a sulfur mustard-induced skin exposure is well documented in the literature. Upon skin contact and a characteristic latency period, sulfur mustard (SM) causes erythema, blister formation and ulceration, which is associated with wound healing disorders that may require surgical treatment. Here, we present a case report of accidental exposure to SM in a laboratory setting which required surgical treatment of the skin. The case was illustrated at close intervals over a period of two years and underlines that exposure to SM has to be taken into account when typical clinical symptoms occur. Moreover skin grafts appear to be effective in SM-induced non healing skin ulcerations.
引用
收藏
页码:62 / 66
页数:5
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