Prognostic significance of parameters of heart rate variability as a risk factor of development of hypertension

被引:0
作者
Podpalov, V. P. [1 ]
Deev, A. D. [1 ]
Sivakov, V. P. [1 ]
Rosum, L. A. [1 ]
机构
[1] Res Ctr Prevent Med, Moscow 101953, Russia
关键词
hypertension; heart rate variability; prognostication;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Risk factors and parameters of heart rate variability during active orthoclinostatic test in subjects with normal blood pressure were assessed in a 5 year cohort study on 519 individuals. Logistic stepwise regression revealed most informative factors associated with development of hypertension: sex (p=0.029), body mass index (p=0.005), salt sensitivity threshold (p=0.048), dynamics of heart rate during exercise test (p=0.035). Addition of parameters of heart rate variability (dynamics of standard deviation of R-R intervals and of low frequency component of spectrum during active orthoclinostatic test) increased accuracy of prognosis. With the use of constructed models risk profiles were calculated. Thus, parameters of heart rate variability allow to improve prognostic value of a model.
引用
收藏
页码:39 / 42
页数:4
相关论文
共 22 条
  • [1] BUCOLO G, 1973, CLIN CHEM, V19, P476
  • [2] BURSTEIN M, 1970, J LIPID RES, V11, P583
  • [3] Camm AJ, 1996, EUR HEART J, V17, P354
  • [4] Cassano Patricia A., 1990, Annals of Epidemiology, V1, P33
  • [5] Cheung Bernard M. Y., 2002, American Journal of Hypertension, V15, p188A, DOI 10.1016/S0895-7061(02)02781-4
  • [6] FRIEDEWALD WT, 1972, CLIN CHEM, V18, P499
  • [7] INCIDENCE AND PRECURSORS OF HYPERTENSION IN YOUNG-ADULTS - THE FRAMINGHAM OFFSPRING STUDY
    GARRISON, RJ
    KANNEL, WB
    STOKES, J
    CASTELLI, WP
    [J]. PREVENTIVE MEDICINE, 1987, 16 (02) : 235 - 251
  • [8] HASMER DW, 1989, APPL LOGISTIC REGRES, P25
  • [9] KAPLAN NM, 1998, CLIN HYPERTENSION, P444
  • [10] Kleinbaum D. G, 1988, APPL REGRESSION ANAL, V2nd, P102