The microstructure and gelling mechanism of thermo-responsive chitosan hydrogel system

被引：0

作者：

Fan Donghui ^{[1
]}

Zhang Weiying

Gu Qisheng

Xu Zheng

机构：

[1] Tongji Univ, Sch Mat Sci & Technol, Shanghai 200092, Peoples R China

[2] Qisheng Inst Biomat Technol, Shanghai 201106, Peoples R China

来源：

JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION | 2006年 / 21卷 / 02期

关键词：

thermo-responsive chitosan hydrogel system (TRCHS); microstructure; gelling mechanism;

D O I：

暂无

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Thermo-responsive chitosan hydrogel system (TRCHS) was prepared and its microstructure was investigated by scaning electron microscope (SEM) and mercury intrusion poremaster (MIP). Based on analyzing the data, a special porosity property was reported at the first time. Its gelling mechanism was studied by a group of contrast experiments. Results may provide experimental and theoretical supports for how to apply it on tissue engineering scaffold and how to influence or control its essential properties.

引用

页码：109 / 112

页数：4

共 11 条

[1] Novel injectable neutral solutions of chitosan form biodegradable gels in situ [J].

Chenite, A ;

Chaput, C ;

Wang, D ;

Combes, C ;

Buschmann, MD ;

Hoemann, CD ;

Leroux, JC ;

Atkinson, BL ;

Binette, F ;

Selmani, A .

BIOMATERIALS, 2000, 21 (21) :2155-2161

[2] EFFECTS OF SUGARS AND POLYOLS ON THE SOL-GEL TRANSITION OF KAPPA-CARRAGEENAN - CALORIMETRIC STUDY [J].

GEKKO, K ;

MUGISHIMA, H ;

KOGA, S .

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 1987, 9 (03) :146-152

[3]

Lahiji A, 2000, J BIOMED MATER RES, V51, P586

[4] BLOOD COMPATIBILITY AND BIODEGRADABILITY OF PARTIALLY N-ACYLATED CHITOSAN DERIVATIVES [J].

LEE, KY ;

HA, WS ;

PARK, WH .

BIOMATERIALS, 1995, 16 (16) :1211-1216

[5] The bone regenerative effect of platelet-derived growth factor-BB delivered with a chitosan/tricalcium phosphate sponge carrier [J].

Lee, YM ;

Park, YJ ;

Lee, SJ ;

Ku, Y ;

Han, SB ;

Klokkevold, PR ;

Chung, CP .

JOURNAL OF PERIODONTOLOGY, 2000, 71 (03) :418-424

[6] Biocompatibility of thermosensitive chitosan-based hydrogels: an in vivo experimental approach to injectable biomaterials [J].

Molinaro, G ;

Leroux, JC ;

Damas, J ;

Adam, A .

BIOMATERIALS, 2002, 23 (13) :2717-2722

[7]

Park YJ, 2000, BIOMATERIALS, V21, P153

[8] Controlled release of platelet-derived growth factor-BB from chondroitin sulfate-chitosan sponge for guided bone regeneration [J].

Park, YJ ;

Lee, YM ;

Lee, JY ;

Seol, YJ ;

Chung, CP ;

Lee, SJ .

JOURNAL OF CONTROLLED RELEASE, 2000, 67 (2-3) :385-394

[9] In vitro and in vivo degradation of films of chitin and its deacetylated derivatives [J].

Tomihata, K ;

Ikada, Y .

BIOMATERIALS, 1997, 18 (07) :567-575

[10] In vitro degradation rates of partially N-acetylated chitosans in human serum [J].

Varum, KM ;

Myhr, MM ;

Hjerde, RJN ;

Smidsrod, O .

CARBOHYDRATE RESEARCH, 1997, 299 (1-2) :99-101

← 1 2 →