Dendritic maleimide functionalization of core-shell (γ-Fe2O3/polymer) nanoparticles for efficient bio-immobilization

被引:7
作者
Mitcova, L. [1 ,2 ]
Rahma, H. [1 ,2 ]
Buffeteau, T. [1 ,2 ]
Clerac, R. [3 ,4 ]
Vellutini, L. [1 ,2 ]
Heuze, K. [1 ,2 ]
机构
[1] Univ Bordeaux, ISM UMR 5255, F-33400 Talence, France
[2] CNRS, ISM UMR 5255, F-33400 Talence, France
[3] CNRS, CRPP, UPR 8641, F-33600 Pessac, France
[4] Univ Bordeaux, CRPP, UPR 8641, F-33600 Pessac, France
关键词
IRON-OXIDE NANOPARTICLES; MAGNETIC NANOPARTICLES; GOLD NANOPARTICLES; SURFACE; STRATEGIES; DENDRIMERS; RESONANCE; POLYMERS; DESIGN; CELL;
D O I
10.1039/c5ra17928a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new route for the preparation of stable and water-dispersible core-shell gamma-Fe2O3/polymer MNPs has been developed in order to ensure a selective and covalent immobilization of biomolecules using maleimide-thiol coupling chemistry. A high maleimide functionalization was achieved by the grafting of dendritic coupling agent via a convergent approach.
引用
收藏
页码:88574 / 88577
页数:4
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