Genetics of panic disorder on the Faroe Islands: a replication study of chromosome 9 and panic disorder

被引：5
作者：
Wang, AG
Dahl, HA
Vang, M
Als, TD
Ewald, H
Kruse, TA
Mors, O
机构：
[1] Copenhagen Univ Hosp, Dept Psychiat, HS Amager Hosp, DK-2300 Copenhagen S, Denmark
[2] Natl Hosp, Dept Psychiat, Torshavn, Faroe Islands, Denmark
[3] Odense Univ Hosp, Dept Clin Biochem & Genet, DK-5000 Odense, Denmark
[4] Hosp Psychiat, Ctr Basic Psychiat Res, Aarhus, Denmark
来源：
PSYCHIATRIC GENETICS | 2006年 / 16卷 / 03期
关键词：
chromosome; 9; Faroe Islands; genetic isolate; Iceland; panic disorder;
D O I：
10.1097/01.ypg.0000199445.77291.ab
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Objective The population of the Faroe Islands in the North Atlantic Ocean is likely to have the same ancestry as the Icelandic population. An Icelandic study on Panic Disorder has found some evidence for a loci on chromosome 9. Methods On the Faroe Islands we have an ongoing genetic project concerning panic disorder among other psychiatric disorders. We searched for shared alleles and haplotypes in distantly related cases from the isolated and recently found population of the Faroe Islands, using 26 more or less evenly distributed microsatellite markers on chromosome 9, with emphasis on the candidate region identified in the Icelandic study. Results We have not been able to replicate the Icelandic results. Owing to the study design and sample size, we would not be able to detect areas with Small impact
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页码：99 / 104
页数：6
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