Sulfated polyborate as Bronsted acid catalyst for Knoevenagel condensation

被引：4

作者：

Ganwir, Prerna ^{[1
,2
]}

Bandivadekar, Priyanka ^{[1
]}

Chaturbhuj, Ganesh ^{[1
]}

机构：

[1] Inst Chem Technol, Dept Pharmaceut Sci & Technol, Mumbai 400019, India

[2] Dr Bhanuben Nanavati Coll Pharm, Dept Pharmaceut Chem, Vile Parle West, Mumbai 400056, India

来源：

RESULTS IN CHEMISTRY | 2022年 / 4卷

关键词：

Sulfated polyborate; Aldehydes; ketones; Knoevenagel condensation; Active methylene; EFFICIENT CATALYST; REUSABLE CATALYST; CYCLOADDITION; PROTOCOL; CHLORIDE;

D O I：

10.1016/j.rechem.2022.100632

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have developed the use of Bronsted acid for Knoevenagel condensation. Sulfated polyborate has been used for efficient Knoevenagel condensation of aromatic, heterocyclic, alpha,beta-unsaturated, and aliphatic aldehydes in the ecologically friendly ethanol: water (1:1) mixture as solvent at 70 degrees C. It took less time for certain aldehydes to react with active methylenes. The present method demonstrated significant benefits in terms of first-time use of Bronsted acid catalyst, mild reaction conditions, and better product yields.

引用

页数：4

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