Antimicrobial susceptibility of Clostridium difficile isolated from animals and humans in Brazil

被引：5

作者：

Silveira Silva, Rodrigo Otavio ^{[1
]}

Oliveira Junior, Carlos Augusto ^{[1
]}

Diniz, Amanda Nadia ^{[1
]}

Alves, Guilherme Guerra ^{[1
]}

Carvalho Guedes, Roberto Mauricio ^{[1
]}

Vilela, Eduardo Garcia ^{[2
]}

Faria Lobato, Francisco Carlos ^{[1
]}

机构：

[1] Univ Fed Minas Gerais, Escola Vet, BR-31270901 Belo Horizonte, MG, Brazil

[2] Univ Fed Minas Gerais, Fac Med, BR-31270901 Belo Horizonte, MG, Brazil

来源：

CIENCIA RURAL | 2014年 / 44卷 / 05期

关键词：

nosocomial diarrhea; pseudomembranous colitis; resistance; DIARRHEA; PERFRINGENS; INFECTION; PREVALENCE; RESISTANCE; TOXINOTYPE; HORSES;

D O I：

10.1590/S0103-84782014000500013

中图分类号：

S3 [农学（农艺学）];

学科分类号：

0901 ;

摘要：

The objective of this study was to evaluate antimicrobial susceptibility in Clostridium difficile strains isolated from animals and humans in Brazil. The 54 C. difficile strains used were isolated from stool samples from piglets (n=16), dogs (n=13), humans (n=13), foals (n=8) calves (n=2), an ocelot (n=1) and a maned wolf (n=1). Antimicrobial susceptibility was determined using the serial plate agar dilution method for penicillin, florfenicol, oxytetracycline, erythromycin, vancomycin, metronidazole and tylosin. The C. difficile strains assessed were susceptible to metronidazole and vancomycin. Florfenicol resistance was rarely observed; 52 (96.4%) strains were sensitive to this antimicrobial. Five (9.3%), five (9.3%), 14 (25.9%) and 20 (37.0%) strains were resistant to oxytetracycline, penicillin, tylosin and erythromycin respectively.

引用

页码：841 / 846

页数：6

共 33 条

[1] Characterization of Clostridium difficile strains isolated from immunosuppressed inpatients in a hospital in Rio de Janeiro, Brazil [J].

Balassiano, Ilana T. ;

Miranda, Karla R. ;

Boente, Renata F. ;

Pauer, Heidi ;

Oliveira, Ivi Cristina M. ;

Santos-Filho, Joaquim ;

Amorim, Efigenia L. T. ;

Canine, Gerson A. ;

Souza, Cristina F. ;

Gomes, Mariza Z. R. ;

Ferreira, Eliane O. ;

Brazier, Jon S. ;

Domingues, Regina M. C. P. .

ANAEROBE, 2009, 15 (03) :61-64

[2] Clostridum difficile diarrhea:: infection control in horses [J].

Båverud, V .

VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE, 2004, 20 (03) :615-+

[3] Clostridium difficile:: prevalence in horses and environment, and antimicrobial susceptibility [J].

Bâverud, V ;

Gustafsson, A ;

Franklin, A ;

Aspán, A ;

Gunnarsson, A .

EQUINE VETERINARY JOURNAL, 2003, 35 (05) :465-471

[4] Clostridium difficile infections in animals with special reference to the horse -: A review [J].

Båverud, V .

VETERINARY QUARTERLY, 2002, 24 (04) :203-219

[5] Fatal enterocolitis in Asian elephants (Elephas maximus) caused by Clostridium difficile [J].

Bojesen, Anders Miki ;

Olsen, Katharina E. P. ;

Bertelsen, Mads F. .

VETERINARY MICROBIOLOGY, 2006, 116 (04) :329-335

[6]

BRASIL Ministerio da Agricultura e da Reforma Agraria, 1998, MIN AGR REF AGR

[7]

CLSI (CLINICAL AND LABORATORY STANDARDS INSTITUTE), 2011, 21 INFORM SUPPLEMENT, V31, P111

[8] CORRELATION BETWEEN SEROGROUP AND SUSCEPTIBILITY TO CHLORAMPHENICOL, CLINDAMYCIN, ERYTHROMYCIN, RIFAMPICIN AND TETRACYCLINE AMONG 308 ISOLATES OF CLOSTRIDIUM-DIFFICILE [J].

DELMEE, M ;

AVESANI, V .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1988, 22 (03) :325-331

[9] INVITRO SUSCEPTIBILITY OF CLOSTRIDIUM-DIFFICILE ISOLATES FROM PATIENTS WITH ANTIBIOTIC-ASSOCIATED DIARRHEA OR COLITIS [J].

DZINK, J ;

BARTLETT, JG .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1980, 17 (04) :695-698

[10]

EUCAST (EUROPEAN COMMITTEE ON ANTIMICROBIAL SUSCEPTIBILITY TESTING), 2011, BR TABL INT MICS ZON, V3.1

← 1 2 3 4 →