Even in the modern era of advanced diagnostic imaging, improved antibiotic therapy and potentially curative surgery, infective endocarditis remains a serious disease with high rates of morbidity and mortality. Reasons for such a persistently poor outcome may be represented by the changing epidemiology and microbiology, with new groups of patients at risk and new and more aggressive microorganisms. However, the inadequate use of both diagnostic (blood cultures and echocardiography) and therapeutic (antibiotics and surgery) means can influence the generally delayed diagnosis and poor prognosis seen in patients with infective endocarditis. We tried to identify the critical points in the management of patients with infective endocarditis and to elaborate a formal multidisciplinary approach based on the strict collaboration of specialists in infectious diseases, microbiology, cardiology and cardiac surgery. We hypothesized that this approach could increase the adherence to the published guidelines, and could represent a means to improve the outcome of patients with infective endocarditis.
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页码:659 / 668
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[1]
Baddour LM, 2005, CIRCULATION, V111, pE394, DOI 10.1161/CIRCULATIONAHA.105.165564
机构:Univ Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Botelho-Nevers, Elisabeth
;
Thuny, Franck
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Hop de la Timone, Serv Cardiol Adulte, Marseille, FranceUniv Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Thuny, Franck
;
Casalta, Jean Paul
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机构:Univ Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Casalta, Jean Paul
;
Richet, Herve
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机构:Univ Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Richet, Herve
;
Gouriet, Frederique
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机构:Univ Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Gouriet, Frederique
;
Collart, Frederic
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Hop de la Timone, Serv Chirurg Cardiaque, Marseille, FranceUniv Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Collart, Frederic
;
Riberi, Alberto
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Hop de la Timone, Serv Chirurg Cardiaque, Marseille, FranceUniv Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Riberi, Alberto
;
Habib, Gilbert
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Hop de la Timone, Serv Cardiol Adulte, Marseille, FranceUniv Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Habib, Gilbert
;
Raoult, Didier
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机构:
Univ Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, FranceUniv Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
机构:Univ Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Botelho-Nevers, Elisabeth
;
Thuny, Franck
论文数: 0引用数: 0
h-index: 0
机构:
Hop de la Timone, Serv Cardiol Adulte, Marseille, FranceUniv Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Thuny, Franck
;
Casalta, Jean Paul
论文数: 0引用数: 0
h-index: 0
机构:Univ Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Casalta, Jean Paul
;
Richet, Herve
论文数: 0引用数: 0
h-index: 0
机构:Univ Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Richet, Herve
;
Gouriet, Frederique
论文数: 0引用数: 0
h-index: 0
机构:Univ Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Gouriet, Frederique
;
Collart, Frederic
论文数: 0引用数: 0
h-index: 0
机构:
Hop de la Timone, Serv Chirurg Cardiaque, Marseille, FranceUniv Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Collart, Frederic
;
Riberi, Alberto
论文数: 0引用数: 0
h-index: 0
机构:
Hop de la Timone, Serv Chirurg Cardiaque, Marseille, FranceUniv Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Riberi, Alberto
;
Habib, Gilbert
论文数: 0引用数: 0
h-index: 0
机构:
Hop de la Timone, Serv Cardiol Adulte, Marseille, FranceUniv Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France
Habib, Gilbert
;
Raoult, Didier
论文数: 0引用数: 0
h-index: 0
机构:
Univ Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, FranceUniv Aix Marseille 2, Unite Rickettsies, CNRS UMR 6236, IFR 48,Fac Med,Lab Microbiol, F-13385 Marseille 5, France