A compact low-noise broadband digital picoammeter architecture

被引:8
作者
Crescentini, M. [1 ]
Tartagni, M. [1 ,2 ]
Morgan, H. [3 ,4 ]
Traverso, P. A. [5 ]
机构
[1] Univ Bologna, Dept Elect Elect & Informat Engn DEI Guglielmo Ma, Cesena Campus, I-47521 Cesena, Italy
[2] Univ Bologna, Adv Res Ctr Elect Syst ARCES, Cesena Campus, I-47521 Cesena, Italy
[3] Univ Southampton, Elect & Comp Sci, Southampton SO17 1BJ, Hants, England
[4] Univ Southampton, Inst Life Sci, Southampton SO17 1BJ, Hants, England
[5] Univ Bologna, Dept Elect Elect & Informat Engn DEI Guglielmo Ma, Bologna Campus, I-40136 Bologna, Italy
基金
英国工程与自然科学研究理事会;
关键词
Ammeter; Low-current measurement; Current; Leakage currents; Charge-sensitive amplifier; Low-noise amplifier; Femto-ampere; TRANSIMPEDANCE AMPLIFIER; SENSING PLATFORM; FRONT-END;
D O I
10.1016/j.measurement.2016.12.040
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A low-noise (<= 44 fA/root Hz), broadband (>= 100 kHz) compact architecture and related operation solutions are proposed for portable and low-cost time-domain acquisition of currents with effective resolution in the order of 1 pA and below. The front-end architecture is based on an integrating-differentiating scheme to achieve the optimal performance in terms of input-referred equivalent noise, but it overcomes the typical noise/bandwidth trade-off by making the sampling frequency of the AID conversion independent from the rate at which the analog front-end is reset. In order to strongly mitigate the main drawback, i.e., the introduction in the system of an inherent time-variance, a Track-and-Hold circuit synchronized with the reset is exploited. For validation purposes, a dual-channel prototype was implemented in a low-cost CMOS technology. The prototype is characterized by standard figures of merit and is experimentally validated by two simple case studies, which are typical of practical applications. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:194 / 204
页数:11
相关论文
共 23 条
[1]  
Ang K.-W., 2008, IEEE PHOTONIC TECH L, V20, P754
[2]  
[Anonymous], 2000, IEEE STAND TERM TEST
[3]  
[Anonymous], 2014, KEYSIGHT B2980A SERI
[4]  
Bennati Marco, 2009, 2009 IEEE International Solid-State Circuits Conference (ISSCC 2009), P348, DOI 10.1109/ISSCC.2009.4977451
[5]   Design and characterization of a current sensing platform for silicon-based nanopores with integrated tunneling nanoelectrodes [J].
Carminati, Marco ;
Ferrari, Giorgio ;
Ivanov, Aleksandar P. ;
Albrecht, Tim ;
Sampietro, Marco .
ANALOG INTEGRATED CIRCUITS AND SIGNAL PROCESSING, 2013, 77 (03) :333-343
[6]  
Crescentini M., 2009, Proceedings of the 3rd International Workshop on Advances in Sensors and Interfaces, P163
[7]   A Low-Noise Transimpedance Amplifier for BLM-Based Ion Channel Recording [J].
Crescentini, Marco ;
Bennati, Marco ;
Saha, Shimul Chandra ;
Ivica, Josip ;
de Planque, Maurits ;
Morgan, Hywel ;
Tartagni, Marco .
SENSORS, 2016, 16 (05)
[8]   A Distributed Amplifier System for Bilayer Lipid Membrane (BLM) Arrays With Noise and Individual Offset Cancellation [J].
Crescentini, Marco ;
Thei, Frederico ;
Bennati, Marco ;
Saha, Shimul ;
de Planque, Maurits R. R. ;
Morgan, Hywel ;
Tartagni, Marco .
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, 2015, 9 (03) :334-344
[9]   Noise Limits of CMOS Current Interfaces for Biosensors: A Review [J].
Crescentini, Marco ;
Bennati, Marco ;
Carminati, Marco ;
Tartagni, Marco .
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, 2014, 8 (02) :278-292
[10]   A 155-dB Dynamic Range Current Measurement Front End for Electrochemical Biosensing [J].
Dai, Shanshan ;
Perera, Rukshan T. ;
Yang, Zi ;
Rosenstein, Jacob K. .
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, 2016, 10 (05) :935-944