Acute kidney injury after transcatheter, aortic valve implantation: Incidence, predictors and impact on mortality

被引:108
作者
Elhmidi, Yacine [1 ]
Bleiziffer, Sabine [1 ]
Deutsch, Marcus-Andre [1 ]
Krane, Markus [1 ]
Mazzitelli, Domenico [1 ]
Lange, Ruediger [1 ]
Piazza, Nicolo [1 ,2 ]
机构
[1] German Heart Ctr, Clin Cardiovasc Surg, D-80636 Munich, Germany
[2] McGill Univ, Ctr Hlth, Dept Intervent Cardiol, Montreal, PQ, Canada
关键词
Acute kidney injury; TAVR; RIFLE criteria; ACADEMIC RESEARCH CONSORTIUM; PERCUTANEOUS CORONARY INTERVENTION; END-POINT DEFINITIONS; ACUTE-RENAL-FAILURE; REPLACEMENT; RISK;
D O I
10.1016/j.acvd.2014.01.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
There is a paucity of data describing acute kidney injury (AKI) following transcatheter aortic valve implantation and its impact on mortality remains unknown. We therefore evaluate the incidence, predictors and impact of AKI following transcatheter aortic valve implantation. We searched MEDLINE for studies from 2008 to 2013, evaluating AKI after transcatheter aortic valve implantation. All studies were compared according to the incidence, predictors and impact of AKI following transcatheter aortic valve implantation. AKI was diagnosed according to the Valve Academic Research Consortium definition using the RIFLE criteria. Thirteen studies with more than 1900 patients were included. AKI occurred in 8.3-57% of the patients. The following factors were associated with AKI: blood transfusion; transapical access; preoperative creatinine concentration; peripheral vascular disease; hypertension; and procedural bleeding events. The 30-day mortality rate in patients with AKI ranged from 13.3% to 44.4% and was 2-6-fold higher than in patients without AKI. The amount of contrast agent used was not associated with the occurrence of AKI. AKI is a common complication, with an incidence of 8.3-57% following transcatheter aortic valve implantation. Patients with AKI had higher 30-day and late mortality rates. However, AKI was related to the amount of contrast volume used in only one study. (C) 2014 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:133 / 139
页数:7
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