A Patient With Acute Myeloblastic Leukemia who Presented With Conus Medullaris Syndrome and Review of the Literature

被引:10
作者
Olcay, Lale [1 ]
Aribas, Bilgin Kadri [2 ]
Gokce, Mustafa [3 ]
机构
[1] Dr Abdurrahman Yurtaslan Ankara Oncol Training &, Div Pediat Hematol, TR-06200 Ankara, Turkey
[2] Dr Abdurrahman Yurtaslan Ankara Oncol Training &, Div Radiol, TR-06200 Ankara, Turkey
[3] Kahramanmaras Sutcu Imam Univ, Fac Med, Dept Neurol, Kahramanmaras, Turkey
关键词
AML; conus medullaris syndrome; cauda equina syndrome; CAUDA-EQUINA SYNDROME; ACUTE MYELOID-LEUKEMIA; GRANULOCYTIC SARCOMA; BACK-PAIN; INVOLVEMENT; SPINE; CHLOROMAS; RECURRENT; RELAPSE;
D O I
10.1097/MPH.0b013e31819ed24b
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In childhood, the conus medullaris syndrome owing to leukemia is rare. Here, a 12-year-old boy with acute myeloblastic leukemia, maxillary mass, and conus medullaris syndrome is reported. A biopsy from the maxillary mass revealed "granulocytic sarcoma." Lumbosacral magnetic resonance imaging revealed clumped and thickened cauda equina nerve roots, epidural and periradicular diffuse soft tissue, which was enhanced with gadolinium. Cerebrospinal fluid revealed elevated protein but no cells. Chemotherapy and local radiotherapy for both the face and the spine, yielded bone marrow remission and abatement in neurologic and radiologic findings, but he developed bone marrow relapse and died because of sepsis.
引用
收藏
页码:440 / 447
页数:8
相关论文
共 36 条
  • [1] Atesoglu EB, 2007, TURK J HEMATOL, V24, P28
  • [2] Myelopathy due to intrathecal chemotherapy - Report of six cases
    Bay, A
    Oner, AF
    Etlik, O
    Yilmaz, C
    Caksen, H
    [J]. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2005, 27 (05) : 270 - 272
  • [3] Behm FG, 2006, CHILDHOOD LEUKEMIAS, 2ND EDITION, P150
  • [4] BOJSENMOLLER M, 1983, ACTA PATH MICRO IM A, V91, P209
  • [5] Chim CS, 2001, HAEMATOLOGICA, V86, P1117
  • [6] Chouchary D R, 2006, J Assoc Physicians India, V54, P897
  • [7] Cohen ME, 2006, PEDIAT NEUROLOGY PRI, V2, P1687
  • [8] Imaging features of leptomeningeal metastases
    Collie, DA
    Brush, JP
    Lammie, GA
    Grant, R
    Kunkler, I
    Leonard, R
    Gregor, A
    Sellar, RJ
    [J]. CLINICAL RADIOLOGY, 1999, 54 (11) : 765 - 771
  • [9] Dalton SR, 2001, ARCH PATHOL LAB MED, V125, P1385
  • [10] Granulocytic sarcoma of the spine in nonleukemic patients: Report of three cases
    Deme, S
    Deodhare, SS
    Tucker, WS
    Bilbao, JM
    [J]. NEUROSURGERY, 1997, 40 (06) : 1283 - 1287