Silicon directed ipso-substitution of polymer bound arylsilanes: Preparation of biaryls via the Suzuki cross-coupling reaction

被引：95

作者：

Han, YX

Walker, SD

Young, RN

机构：

[1] Department of Medicinal Chemistry, Merck Frosst Ctr. Therapeut. Res., Pointe-Claire-Dorval, Que. H9R 4P8

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 16期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/0040-4039(96)00364-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method for attaching haloarylsilanes to polymer support was developed. The polymer bound arylhalides were reacted with a variety of ArB(OH)(2) under the Suzuki cross-coupling reaction conditions and the coupled resins werecleaved by different electrophiles to give ipso-substitution products in good yields. Copyright (C) 1996 Elsevier Science Ltd.

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页码：2703 / 2706

页数：4

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