Anti-Ulcer Activity of Essential Oil Constituents

被引：51
作者：
Oliveira, Francisco de Assis [1 ]
Andrade, Luciana Nalone [2 ]
Vieira de Sousa, Elida Batista [3 ]
de Sousa, Damiao Pergentino [2 ,3 ]
机构：
[1] Univ Fed Piaui, Coordenacao Curso Farm, BR-64049550 Teresina, PI, Brazil
[2] Univ Fed Sergipe, Dept Farm, BR-49100000 Sao Cristovao, SE, Brazil
[3] Univ Fed Paraiba, Dept Ciencias Farmaceut, BR-58051970 Joao Pessoa, Paraiba, Brazil
来源：
MOLECULES | 2014年 / 19卷 / 05期
关键词：
ulcer; gastroprotective; essential oil; monoterpene; phenylpropanoid; anti-inflammatory; antiulcerogenic; natural products; GASTRIC-MUCOSAL INJURY; NF-KAPPA-B; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; XANTHINE OXIDASE SYSTEM; TUMOR-NECROSIS-FACTOR; PEPTIC-ULCER DISEASE; TEA TREE OIL; GASTROPROTECTIVE ACTIVITY; NIGELLA-SATIVA; NITRIC-OXIDE;
D O I：
10.3390/molecules19055717
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Essential oils have attracted considerable worldwide attention over the last few decades. These natural products have wide-ranging pharmacological activities and biotechnological applications. Faced with the need to find new anti-ulcer agents and the great effort on the development of drugs for the treatment of ulcers, in this review, the anti-ulcer activities of 21 bioactive compounds found in essential oils are discussed.
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页码：5717 / 5747
页数：31
相关论文
共 209 条
[91]  
Keshvari M, 2013, ARYA ATHEROSCLER, V9, P280
[92]   Synthesis, pharmacological activity and hydrolytic behavior of glyceride prodrugs of ibuprofen [J].
Khan, MSY ;
Akhter, M .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2005, 40 (04) :371-376
[93]   Regulatory Effect of Cinnamaldehyde on Monocyte/Macrophage-Mediated Inflammatory Responses [J].
Kim, Byung Hun ;
Lee, Yong Gyu ;
Lee, Jaehwi ;
Lee, Joo Young ;
Cho, Jae Youl .
MEDIATORS OF INFLAMMATION, 2010, 2010
[94]   Antianaphylactic properties of eugenol [J].
Kim, HM ;
Lee, EH ;
Kim, CY ;
Chung, JG ;
Kim, SH ;
Lim, JP ;
Shin, TY .
PHARMACOLOGICAL RESEARCH, 1997, 36 (06) :475-480
[95]   Bisabolangelone inhibits dendritic cell functions by blocking MAPK and NF-κB signaling [J].
Kim, Hyung Sook ;
Lee, Young June ;
Lee, Hong Kyung ;
Kim, Ji Sung ;
Park, Yunsoo ;
Kang, Jong Soon ;
Hwang, Bang Yeon ;
Hong, Jin Tae ;
Kim, Youngsoo ;
Han, Sang-Bae .
FOOD AND CHEMICAL TOXICOLOGY, 2013, 59 :26-33
[96]   Inhibitory effects of (-)-α-bisabolol on LPS-induced inflammatory response in RAW264.7 macrophages [J].
Kim, Seungbeom ;
Jung, Eunsun ;
Kim, Jang-Hyun ;
Park, Young-Ho ;
Lee, Jongsung ;
Park, Deokhoon .
FOOD AND CHEMICAL TOXICOLOGY, 2011, 49 (10) :2580-2585
[97]   Time-dependent aroma changes in breast milk after oral intake of a pharmacological preparation containing 1,8-cineole [J].
Kirsch, Frauke ;
Beauchamp, Jonathan ;
Buettner, Andrea .
CLINICAL NUTRITION, 2012, 31 (05) :682-692
[98]   Antiulcerogenic activity of extract, fractions, and some compounds obtained from Polygala cyparissias St. Hillaire & Moquin (Polygalaceae) [J].
Klein, Luiz Carlos, Jr. ;
Gandolfi, Renan Becker ;
Santin, Jose Roberto ;
Lemos, Marivane ;
Cechinel Filho, Valdir ;
de Andrade, Sergio Faloni .
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2010, 381 (02) :121-126
[99]  
Klopell FC, 2007, Z NATURFORSCH C, V62, P537
[100]   Teprenone promotes the healing of acetic acid-induced chronic gastric ulcers in rats by inhibiting neutrophil infiltration and lipid peroxidation in ulcerated gastric tissues [J].
Kobayashi, T ;
Ohta, Y ;
Yoshino, J ;
Nakazawa, S .
PHARMACOLOGICAL RESEARCH, 2001, 43 (01) :23-30
567891011121314