The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds

被引：57

作者：

Barros, Lillian ^{[1
]}

Calhelha, Ricardo C. ^{[1
,2
]}

Queiroz, Maria Joao R. P. ^{[2
]}

Santos-Buelga, Celestino ^{[3
]}

Santos, Elandia A. ^{[4
]}

Regis, Wiliam C. B. ^{[4
]}

Ferreira, Isabel C. F. R. ^{[1
]}

机构：

[1] Polytech Inst Braganca, ESA, Mt Res Ctr CIMO, P-5301855 Braganca, Portugal

[2] Univ Minho, Ctr Chem, P-4710057 Braga, Portugal

[3] Univ Salamanca, Fac Farm, GIP USAL, Salamanca 37007, Spain

[4] Pontificia Univ Catolica Minas Gerais PUCMinas, Inst Ciencias Biol & Saude, Programa Pos Grad Biol Vertebrados, BR-3053590 Belo Horizonte, MG, Brazil

来源：

INDUSTRIAL CROPS AND PRODUCTS | 2015年 / 76卷

关键词：

Euterpe oleracea; Phenolic characterization; Antioxidant properties; Antitumor activity; CHEMICAL-CHARACTERIZATION; ANTIOXIDANT PROPERTIES; SCAVENGING CAPACITY; FRUITS; PULP; RICH;

D O I：

10.1016/j.indcrop.2015.05.086

中图分类号：

S2 [农业工程];

学科分类号：

0828 ;

摘要：

The Euterpe oleracea Mart. (acai) is a plant from the Amazon region, classified as "super fruit" because of its various functional properties. However, limited investigation has been performed on gal by-products, such as seeds. Therefore, the aim of this work was to characterized the phenolic compounds of the aqueous extract of gal seeds and further evaluate its bioactivity (antioxidant and cytotoxic activities). Only proanthocyanidins were detected, being a B-type (epi) catechin tetramer the most abundant; however, procyanidin trimmers were the most predominant form. Apt seeds extract revealed a high antioxidant (EC50 ranging from 3.6 to 19.4 mu g/mL) and cytotoxic activity, being more effective in the cervical carcinoma cell line (HeLa; GI(50) =18 mu g/mL); it did not show toxicity for non-tumor cells. Acai seeds are considered a waste and could have an added economic benefit, through the extraction of natural antioxidants, particularly proanthocyanidins, that could find applications in food and pharmaceutical industries. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：318 / 322

页数：5

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