Long-term survival and prognostic implications after coronary artery bypass grafting in Chinese patients with coronary artery disease

被引:1
|
作者
Hsiung, Ming C.
Wei, Jeng
Chang, Chung-Yi
Chuang, Yi-Cheng
Lee, Kuo-Chen
Sue, Sung-How
Chou, Yi-Pen
Hsiung, Richard
Shih, Hui-Chuan
Huang, Chien-Ming
Yin, Wei-Hsian
Young, Mason S.
Tung, Tao-Hsin [1 ]
机构
[1] Cheng Hsin Gen Hosp, Div Cardiol, Dept Med, Taipei 112, Taiwan
[2] Cheng Hsin Gen Hosp, Div Cardiovasc Surg, Taipei 112, Taiwan
[3] Cheng Hsin Gen Hosp, Dept Anaesthesiol, Taipei 112, Taiwan
[4] Kaohsiung Mil Gen Hosp, Dept Nursing, Kaohsiung, Taiwan
[5] Cheng Hsin Gen Hosp, Dept Med Res & Educ, Taipei 112, Taiwan
关键词
coronary artery bypass grafting; gender difference; prognostic factors; survival;
D O I
10.2143/AC.61.5.2017766
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives-This hospital-based study was conducted to determine the survival rates of patients after coronary artery bypass grafting (CABG) surgery and the associated prognostic factors related to all-cause mortality during a 7-year follow-up in Taiwan. Methods and results-Between January 1997 and December 2003, the medical records of 1877 patients who underwent primary, isolated CABG surgery were studied. The Kaplan-Meier method was used to estimate survival. Multiple Cox regression was used to investigate the independence of prognostic factors associated with all-cause mortality. Of the 1877 patients who underwent CABG surgery, 192 expired during the 7-year study period. The overall patient survival rate was 85.96% (95% CI: 83.74-88.16). Using multiple Cox regression analysis, in addition to female gender, older age at surgery, pulmonary oedema, longer ischaemic time, longer cardiopulmonary bypass time, and poorer postoperative left ventricular ejection fraction were significant factors associated with all-cause mortality for both men and women. Associated prognostic factors varied by gender. For men, smoking (RR = 2.82,95% CI: 1.06-4.16), respiratory failure (RR = 6.88,95% CI: 3.29-14.40) and cardiogenic shock (RR = 4.04, 95% CI: 2.13-7.67) were significantly related to all-cause mortality, but not for women. Sepsis (RR = 8.97,95% CI: 1.19-19.81) and ICU stay (RR = 1.03,95% CI: 1.0 1 1.05) were significantly related to all-cause mortality among female patients only. Conclusions-Several gender-related differences were noted pertaining to all-cause mortality and the relationships between smoking, sepsis, respiratory failure, cardiogenic shock, and ICU stay.
引用
收藏
页码:519 / 524
页数:6
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