Maternal Immunization

被引：100
作者：
Chu, Helen Y. [1 ]
Englund, Janet A. [2 ]
机构：
[1] Univ Washington, Dept Med, Div Allergy & Infect Dis, Washington, DC USA
[2] Seattle Childrens Hosp, Div Infect Dis, Dept Pediat, Washington, DC USA
来源：
CLINICAL INFECTIOUS DISEASES | 2014年 / 59卷 / 04期
基金：
美国国家卫生研究院;
关键词：
maternal immunization; influenza; tetanus; diphtheria; pertussis; INFLUENZAE TYPE-B; PNEUMOCOCCAL POLYSACCHARIDE VACCINE; SYNCYTIAL VIRUS-INFECTION; PERTUSSIS TDAP IMMUNIZATION; PROTEIN CONJUGATE VACCINE; PREGNANT-WOMEN; ADVISORY-COMMITTEE; NEONATAL OUTCOMES; H1N1; INFLUENZA; PRACTICES ACIP;
D O I：
10.1093/cid/ciu327
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Maternal immunization has the potential to protect the pregnant woman, fetus, and infant from vaccine-preventable diseases. Maternal immunoglobulin G is actively transported across the placenta, providing passive immunity to the neonate and infant prior to the infant's ability to respond to vaccines. Currently inactivated influenza, tetanus toxoid, and acellular pertussis vaccines are recommended during pregnancy. Several other vaccines have been studied in pregnancy and found to be safe and immunogenic and to provide antibody to infants. These include pneumococcus, group B Streptococcus, Haemophilus influenzae type b, and meningococcus vaccines. Other vaccines in development for potential maternal immunization include respiratory syncytial virus, herpes simplex virus, and cytomegalovirus vaccines.
引用
收藏
页码：560 / 568
页数：9
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