Molecular detection and phylogenetic analysis of human parechovirus in children with acute gastroenteritis in Iran

被引：0
作者：
Mohammadi, Mehrdad [1 ]
Armin, Shahnaz [2 ]
Piroozmand, Ahmad [3 ,4 ]
机构：
[1] Kashan Univ Med Sci, Sch Med, Dept Microbiol & Immunol, Med Bacteriol, Kashan, Iran
[2] Shaheed Behesti Univ Med Sci, Fac Med, Pediat Infect Res Ctr, Pediat Infect Dis, Tehran, Iran
[3] Kashan Univ Med Sci, Sch Med, Dept Microbiol & Immunol, Med Virol, Kashan, Iran
[4] Kashan Univ Med Sci, Autoimmune Dis Res Ctr, Sch Med, Kasha, Iran
来源：
FUTURE VIROLOGY | 2020年 / 15卷 / 12期
关键词：
acute gastroenteritis; direct genotyping; human parechovirus; Iran; STOOL SAMPLES; HOSPITALIZED CHILDREN; VIRAL GASTROENTERITIS; GENETIC DIVERSITY; HUMAN BOCAVIRUS; AICHI VIRUS; EPIDEMIOLOGY; ENTEROVIRUSES; PREVALENCE; INFECTION;
D O I：
10.2217/fvl-2020-0114
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Aim: Human parechovirus (HPeV) is one of the major causes of acute gastroenteritis in children. Materials & methods: Stool specimens (n = 250) were collected from children aged <= 3 years during 2018-2019. HPeV RNA was detected by reverse transcription-PCR and genotyping by VP1 gene, Rotavirus (RV) screened by ELISA. Results: HPeV was detected in 12% of the cases. The children under 6-months old (64.2%) were a sensitive group and HPeV was more prevalent during January-February (73.3%). The co-infection of HPeV with RV was 50%. All of the sequenced samples belong to the HPeV-1 genotype. Conclusion: HPeV-1 is one of the major causes of acute viral gastroenteritis in children and the co-infection of RV can be an additional infection in some cases.
引用
收藏
页码：783 / 789
页数：8
相关论文
共 37 条
  • [1] Viral Etiologies of Acute Dehydrating Gastroenteritis in Pakistani Children: Confounding Role of Parechoviruses
    Alam, Muhammad Masroor
    Khurshid, Adnan
    Shaukat, Shahzad
    Rana, Muhammad Suleman
    Sharif, Salmaan
    Angez, Mehar
    Nisar, Nadia
    Aamir, Uzma Bashir
    Naeem, Muhammad
    Zaidi, Syed Sohail Zahoor
    [J]. VIRUSES-BASEL, 2015, 7 (01): : 378 - 393
  • [2] Human Parechovirus Genotypes-10,-13 and-15 in Pakistani Children with Acute Dehydrating Gastroenteritis
    Alam, Muhammad Masroor
    Khurshid, Adnan
    Shaukat, Shahzad
    Rana, Muhammad Suleman
    Sharif, Salmaan
    Angez, Mehar
    Nisar, Nadia
    Naeem, Muhammad
    Zaidi, Syed Sohail Zahoor
    [J]. PLOS ONE, 2013, 8 (11):
  • [3] Identification of human parechovirus genotype, HPeV-12, in a paralytic child with diarrhea
    Alam, Muhammad Masroor
    Khurshid, Adnan
    Shaukat, Shahzad
    Sharif, Salmaan
    Rana, Muhammad Suleman
    Angez, Mehar
    Naeem, Muhammad
    Zaidi, Syed Sohail Zahoor
    [J]. JOURNAL OF CLINICAL VIROLOGY, 2012, 55 (04) : 339 - 342
  • [4] Molecular Detection of Human Astrovirus in Children With Gastroenteritis, Northern Italy
    Bergallo, Massimiliano
    Galliano, Ilaria
    Dapra, Valentina
    Rassu, Marco
    Montanari, Paola
    Tovo, Pier-Angelo
    [J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2018, 37 (08) : 738 - 742
  • [5] Parechovirus: an important emerging infection in young infants
    Britton, Philip N.
    Jones, Cheryl A.
    Macartney, Kristine
    Cheng, Allen C.
    [J]. MEDICAL JOURNAL OF AUSTRALIA, 2018, 208 (08) : 365 - +
  • [6] Human Parechovirus Infection in Children in Taiwan: a Retrospective, Single-Hospital Study
    Chang, Jenn-Tzong
    Chen, Yao-Shen
    Chen, Bao-Chen
    Huang, Tsi-Shu
    Chang, Tsung-Hsien
    [J]. JAPANESE JOURNAL OF INFECTIOUS DISEASES, 2018, 71 (04) : 291 - 297
  • [7] Genome and Infection Characteristics of Human Parechovirus Type 1: The Interplay between Viral Infection and Type I Interferon Antiviral System
    Chang, Jenn-Tzong
    Yang, Chih-Shiang
    Chen, Yao-Shen
    Chen, Bao-Chen
    Chiang, An-Jen
    Chang, Yu-Hsiang
    Tsai, Wei-Lun
    Lin, You-Sheng
    Chao, David
    Chang, Tsung-Hsien
    [J]. PLOS ONE, 2015, 10 (02):
  • [8] Diversity and Recombination of Human Parechovirus in Children With Acute Gastroenteritis in Guangzhou, China
    Chen, Hui-fang
    Zheng, Xue-yan
    Chen, Xia-ming
    Shi, Ting-li
    Yao, Yue-xian
    Yuan, Qing
    Chen, Qing
    Yu, Shou-yi
    [J]. JOURNAL OF MEDICAL VIROLOGY, 2015, 87 (02) : 296 - 302
  • [9] Molecular detection of human parechovirus in children with acute gastroenteritis in Guangzhou, China
    Chen, Huifang
    Yao, Yuexian
    Liu, Xie
    Xiao, Ni
    Xiao, Yuan
    Huang, Yanhui
    Chen, Qing
    Yu, Shouyi
    [J]. ARCHIVES OF VIROLOGY, 2014, 159 (05) : 971 - 977
  • [10] Molecular detection and phylogenetic analysis of human parechovirus in individuals with acute diarrhea and healthy controls in Guangzhou, China
    Chen, Xuejiao
    Shi, Tingli
    Huang, Jianhua
    Xiao, Gang
    Huang, Jing
    Xiong, Yiquan
    Li, Xiufen
    Chen, Huifang
    Zheng, Xueyan
    Yu, Shouyi
    Chen, Qing
    [J]. JOURNAL OF MEDICAL VIROLOGY, 2018, 90 (09) : 1444 - 1452
1234