The solubility of bosentan in aqueous-2-propanol mixtures at several temperatures, measurement and data correlation

被引：3

作者：

Barzegar-Jalali, Mohammad ^{[1
,2
]}

Mirheydari, Seyyedeh Narjes ^{[3
]}

Shekaari, Hemayat ^{[4
]}

Martinez, Fleming ^{[5
]}

Jouyban, Abolghasem ^{[6
,7
,8
]}

机构：

[1] Tabriz Univ Med Sci, Res Ctr Pharmaceut Nanotechnol, Tabriz, Iran

[2] Tabriz Univ Med Sci, Fac Pharm, Tabriz, Iran

[3] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz, Iran

[4] Univ Tabriz, Fac Chem, Dept Phys Chem, Tabriz, Iran

[5] Univ Nacl Colombia, Sede Bogota, Grp Invest Farmaceut Fisicoquim, Dept Farm,Fac Ciencias, Bogota, DC, Colombia

[6] Tabriz Univ Med, Pharmaceut Anal Res Ctr, Tabriz, Iran

[7] Tabriz Univ Med, Fac Pharm, Tabriz, Iran

[8] Tabriz Univ Med Sci, Kimia Idea Pardaz Azarbayjan KIPA Sci Based Co, Tabriz, Iran

来源：

PHYSICS AND CHEMISTRY OF LIQUIDS | 2019年 / 57卷 / 05期

关键词：

Solubility; bosentan; 2-propanol; binary solvent mixture; van't Hoff equation; thermodynamic parameters; DEEP EUTECTIC SOLVENTS; SOLUTION THERMODYNAMICS; AQUEOUS-SOLUTIONS; WATER; ACETAMINOPHEN; 2-PROPANOL; 1-PROPANOL; METHANOL; ETHANOL; DRUGS;

D O I：

10.1080/00319104.2018.1499911

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The solubilities of bosentan (BST) in binary aqueous mixtures of 2-propanol at temperatures ranging from 293.15 to 313.15 K were determined using a shake-flask method. The produced data were modelled with the Jouyban-Acree-van't Hoff model and difference between the predicted data and experimental ones were illustrated by percent average relative deviations (%ARD). Moreover, the thermodynamic functions of dissolution for BST in the aqueous 2-propanol solutions were computed which suggest that the dissolution process is endothermic and not spontaneous.

引用

页码：578 / 586

页数：9

共 31 条

[1] Solubility of silybin in aqueous dextran solutions
Bai, TC
Yan, GB
Zhang, HL
Hu, J
[J]. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2005, 50 (05) : 1596 - 1601
[2] Borzouei M, 2018, 2018 23RD ELECTRICAL POWER DISTRIBUTION NETWORK CONFERENCE (EPDC), P1, DOI 10.1109/EPDC.2018.8536300
[3] Centeno NO, REVISION 4 HIPERTENS
[4] Solution thermodynamics and preferential solvation of sulfamethazine in (methanol plus water) mixtures
Delgado, Daniel R.
Almanza, Ovidio A.
Martinez, Fleming
Pena, Maria A.
Jouyban, Abolghasem
Acree, William E., Jr.
[J]. JOURNAL OF CHEMICAL THERMODYNAMICS, 2016, 97 : 264 - 276
[5] Solubility and Solution Thermodynamics of Some Sulfonamides in 1-Propanol + Water Mixtures
Delgado, Daniel R.
Martinez, Fleming
[J]. JOURNAL OF SOLUTION CHEMISTRY, 2014, 43 (05) : 836 - 852
[6] Solubility of 2-Hydroxybenzoic Acid in Water, 1-Propanol, 2-Propanol, and 2-Propanone at (298.2 to 338.2) K and Their Aqueous Binary Mixtures at 298.2 K
Fakhree, Mohammad A. A.
Ahmadian, Somaieh
Panahi-Azar, Vahid
Acree, William E., Jr.
Jouyban, Abolghasem
[J]. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2012, 57 (11) : 3303 - 3307
[7] Computational approaches to determine drug solubility
Faller, Bernard
Ertl, Peter
[J]. ADVANCED DRUG DELIVERY REVIEWS, 2007, 59 (07) : 533 - 545
[8] Measurement and correlation of deferiprone solubility: Investigation of solubility parameter and application of van't Hoff equation and Jouyban-Acree model
Fathi-Azarbayjani, Anahita
Abbasi, Masoumeh
Vaez-Gharamaleki, Jalil
Jouyban, Abolghasem
[J]. JOURNAL OF MOLECULAR LIQUIDS, 2016, 215 : 339 - 344
[9] Measurement and prediction of solubility of paracetamol in water-isopropanol solution. Part 1. Measurement and data analysis
Hojjati, H.
Rohani, S.
[J]. ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2006, 10 (06) : 1101 - 1109
[10] Jouyban A, 2006, PHARMAZIE, V61, P789

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