Directed Additions of 2-Arylpyridines and Related Substrates to Cyclic Imines through Rhodium-Catalyzed C-H Functionalization

被引：49

作者：

Parthasarathy, Kanniyappan ^{[1
]}

Azcargorta, Ane Rebolledo ^{[1
]}

Cheng, Ying ^{[1
]}

Bolm, Carsten ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52056 Aachen, Germany

来源：

ORGANIC LETTERS | 2014年 / 16卷 / 09期

关键词：

N BOND FORMATION; ENANTIOSELECTIVE ADDITION; HETEROAROMATIC-COMPOUNDS; ARYL KETONES; ACTIVATION; ISOCYANATES; ALDEHYDES; AMIDATION; KETIMINES; ALKYNES;

D O I：

10.1021/ol500918t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Rhodium-catalyzed C-H functionalizations have been used for ortho-directed additions of 2-arylpyridines and (hetero)aryl-substituted pyrimidines, isoquinolines, and benzo[h]quinolones to cyclic imines. The resulting amino-functionalized products are formed in good to high yields.

引用

页码：2538 / 2541

页数：4

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