Rapid detection of antimicrobial resistance by MALDI-TOF mass spectrometry

被引：5

作者：

Oviano, Marina ^{[1
]}

Dolores Rojo, Maria ^{[2
]}

Navarro Mari, Jose Maria ^{[2
]}

Bou, German ^{[1
]}

机构：

[1] Complejo Hosp Univ A Coruna, La Coruna, Spain

[2] Complejo Hosp Univ Granada, Granada, Spain

来源：

ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA | 2016年 / 34卷

关键词：

Mass spectrometry; MALDI-TOF; Resistance mechanisms; Rapid detection;

D O I：

10.1016/S0213-005X(16)30189-6

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In recent years, MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry has become established as a first-line diagnostic tool in the identification of microorganisms, including those producing human infections. Rapid detection of antimicrobial resistance is one of the future applications of this technique with the greatest likelihood of success. This review describes the most important studies published in this field and discusses potential future challenges and the clinical application of this technique in the next few years. (C) 2016 Elsevier Espana, S.L.U. All rights reserved.

引用

页码：36 / 41

页数：6

共 45 条

[1]

Bernardo K, 2002, PROTEOMICS, V2, P747, DOI 10.1002/1615-9861(200206)2:6<747::AID-PROT747>3.0.CO

[2]

2-V

[3]

Bou German, 2014, Enferm Infecc Microbiol Clin, V32 Suppl 4, P24, DOI 10.1016/S0213-005X(14)70171-5

[4] Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry To Detect Carbapenem Resistance within 1 to 2.5 Hours [J].