Multi-parameter Hopf-bifurcation in HHM model exposed to ELF electric field

被引:0
|
作者
Jiang, Wang [1 ]
Che Yanqiu [1 ]
Fei Xiangyang [1 ]
Feng, Dong [1 ]
机构
[1] Tianjin Univ, Sch Elect & Automat Engn, Tianjin 300072, Peoples R China
来源
2005 27TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-7 | 2005年
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D O I
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中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The variation of cell trans-membrane voltage exposed to extremely low frequency (ELF) electric field is analyzed; a modified Hodgkin-Huxley model of muscle (HHM) is established by introducing a new parameter denoting the effect of external electric field, and the bifurcation caused by the new parameter as well as leakage conductance and sodium ions anti-electromotive force is studied. The algebra criterion in high dimension equations is employed to perform the analysis of multi-parameter dynamical bifurcation. The results are of biological significance and suggest that the aberration of dynamics in bio-systems may be accounted for diseases caused by electric exposure.
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页码:4646 / 4649
页数:4
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