A highly selective and sensitive fluorescent turn-on sensor for Hg2+ and its application in live cell imaging

被引：97

作者：

Lu, Hua ^{[1
]}

Xiong, Liqin ^{[2
,3
]}

Liu, Hanzhuang ^{[1
]}

Yu, Mengxiao ^{[2
,3
]}

Shen, Zhen ^{[1
]}

Li, Fuyou ^{[2
,3
]}

You, Xiaozeng ^{[1
]}

机构：

[1] Nanjing Univ, State Key Lab Coordinat Chem, Nanjing Natl Lab Microstruct, Nanjing 210093, Peoples R China

[2] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China

[3] Fudan Univ, Adv Mat Lab, Shanghai 200433, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2009年 / 7卷 / 12期

关键词：

N2O TRIDENTATE LIGANDS; DIOXOTUNGSTEN(VI) COMPLEXES; BODIPY DYES; PROBE; IONS; MERCURY; CHEMOSENSOR; DERIVATIVES; HPYRAMOL; CHLORIDE;

D O I：

10.1039/b902912e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A boron-dipyrromethene (BODIPY) derivative containing a tridentate diaza-oxa ligand (8H-BDP) was synthesized as a fluorescent turn-on chemosensor for Hg2+ with high sensitivity (detection limit <= 2 ppb), a rapid response time (<= 5 seconds) and specific selectivity over other cations under physiological conditions and in live cells according to the confocal fluorescence microscopy experiment.

引用

页码：2554 / 2558

页数：5

共 35 条

[1]

[Anonymous], 2001, EPA823F01011 OFF WAT

[2] A sensitive and selective ratiometric near IR fluorescent probe for zinc ions based on the distyryl-bodipy fluorophore [J].

Atilgan, Serdar ;

Ozdemir, Tugba ;

Akkaya, Engin U. .

ORGANIC LETTERS, 2008, 10 (18) :4065-4067

[3] On the development of sensor molecules that display FeIII-amplified fluorescence [J].

Bricks, JL ;

Kovalchuk, A ;

Trieflinger, C ;

Nofz, M ;

Büschel, M ;

Tolmachev, AI ;

Daub, J ;

Rurack, K .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (39) :13522-13529

[4] Hg2+ Selective Fluorescent and Colorimetric Sensor: Its Crystal Structure and Application to Bioimaging [J].

Chen, Xiaoqiang ;

Nam, Seong-Won ;

Jou, Min Jung ;

Kim, Youngmee ;

Kim, Sung-Jin ;

Park, Sungsu ;

Yoon, Juyoung .

ORGANIC LETTERS, 2008, 10 (22) :5235-5238

[5] A Highly Sensitive and Selective OFF-ON Fluorescent Sensor for Cadmium in Aqueous Solution and Living Cell [J].

Cheng, Tanyu ;

Xu, Yuifang ;

Zhang, Shenyi ;

Zhu, Weiping ;

Qian, Xuhong ;

Duan, Liping .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (48) :16160-+

[6] Synthetic fluorescent sensors for studying the cell biology of metals [J].

Domaille, Dylan W. ;

Que, Emily L. ;

Chang, Christopher J. .

NATURE CHEMICAL BIOLOGY, 2008, 4 (03) :168-175

[7] A monostyryl-boradiazaindacene (BODIPY) derivative as colorimetric and fluorescent probe for cyanide ions [J].

Ekmekci, Zeynep ;

Yilmaz, M. Deniz ;

Akkaya, Engin U. .

ORGANIC LETTERS, 2008, 10 (03) :461-464

[8] Highly sensitive fluorescence probes for nitric oxide based on boron dipyrromethene chromophore-rational design of potentially useful bioimaging fluorescence probe [J].

Gabe, Y ;

Urano, Y ;

Kikuchi, K ;

Kojima, H ;

Nagano, T .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (10) :3357-3367

[9] A BODIPY - Borane dyad for the selective complexation of cyanide ion [J].

Huh, Jung Oh ;

Do, Youngkyu ;

Lee, Min Hyung .

ORGANOMETALLICS, 2008, 27 (06) :1022-1025

[10] In vivo monitoring of mercury ions using a rhodamine-based molecular probe [J].

Ko, Sung-Kyun ;

Yang, Young-Keun ;

Tae, Jinsung ;

Shin, Injae .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (43) :14150-14155

← 1 2 3 4 →