Brugada syndrome and sudden cardiac death in children

被引：183

作者：

Priori, SG ^{[1
]}

Napolitano, C

Giordano, U

Collisani, G

Memmi, M

机构：

[1] Fdn Salvatore Maugeri, Inst Ricoveroe & Cura Carattere Sci, Pavia, Italy

[2] ARNAS Sci, Osped Civico Cristina, Div Cardiol, Palermo, Italy

来源：

LANCET | 2000年 / 355卷 / 9206期

关键词：

D O I：

10.1016/S0140-6736(99)05277-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In five children from the same family who died after unexplained cardiac arrest, Brugada syndrome syndrome was suspected based on the transient manifestation of the typical electrocardiogram pattern in one of them. A mutation in the cardiac sodium-channel confirmed the diagnosis of Brugada syndrome, which suggests that this disease may cause sudden death in children.

引用

页码：808 / 809

页数：2

共 5 条

[1]

Brugada J, 1998, CIRCULATION, V97, P457

[2] Developmental selection of var gene expression in Plasmodium falciparum [J].

Chen, QJ ;

Fernandez, V ;

Sundström, A ;

Schlichtherle, M ;

Datta, S ;

Hagblom, P ;

Wahlgren, M .

NATURE, 1998, 394 (6691) :392-395

[3] Brugada syndrome [J].

Grace, AA .

LANCET, 1999, 354 (9177) :445-446

[4] Genetic and molecular basis of cardiac arrhythmias: Impact on clinical management parts I and II [J].

Priori, SG ;

Barhanin, J ;

Hauer, RNW ;

Haverkamp, W ;

Jongsma, HJ ;

Kleber, AG ;

McKenna, WJ ;

Roden, DM ;

Rudy, Y ;

Schwartz, K ;

Schwartz, PJ ;

Towbin, JA ;

Wilde, AM .

CIRCULATION, 1999, 99 (04) :518-528

[5] Genetic and molecular basis of cardiac arrhythmias - Impact on clinical management [J].