Chemotherapy-induced alopecia: psychosocial impact and therapeutic approaches

被引:111
作者
Hesketh, PJ
Batchelor, D
Golant, M
Lyman, GH
Rhodes, N
Yardley, D
机构
[1] Caritas St Elizabeths Med Ctr, Div Hematol Oncol, Boston, MA 02114 USA
[2] Kingston Reg Canc Ctr, Palliat Med & Support Casre Program, Kingston, ON K7L 5P9, Canada
[3] Wellness Community, Santa Monica, CA 90405 USA
[4] Univ Rochester, Med Ctr, James P Wilmot Canc Ctr, Rochester, NY 14642 USA
[5] GlaxoSmithKline, Corp Commercial Mfg R&D, Res Triangle Pk, NC 27709 USA
[6] Sarah Cannon Canc Ctr, Nashville, TN 37203 USA
关键词
alopecia; chemotherapy; cancer; supportive care; quality of life; psychological;
D O I
10.1007/s00520-003-0562-5
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Despite advances in the treatment of many side effects associated with chemotherapy, alopecia remains an issue that is difficult to resolve. Chemotherapy-induced alopecia (CIA) is a condition that can have profound psychosocial and quality-of-life consequences, resulting in anxiety, depression, a negative body image, lowered self-esteem, and a reduced sense of well-being. Patients who fear CIA may sometimes select regimens with less favorable outcomes or may refuse treatment. When supporting patients with CIA, health care providers should use an individualized approach with a focus placed on the actual moment of hair loss. Education, support groups, and self-care strategies are important components of any management approach. No treatment modality for preventing CIA has been clearly shown to be effective. Recent evidence suggests that new scalp hypothermic regimens may be safe and effective. There remains a critical need for effective new approaches to this problem.
引用
收藏
页码:543 / 549
页数:7
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