Complementary, Holistic, and Integrative Medicine: Melatonin

被引：6

作者：

Shamseer, Larissa ^{[1
]}

Vohra, Sunitha ^{[1
]}

机构：

[1] Univ Alberta, Fac Med, Dept Pediat, Edmonton, AB T6G 2M7, Canada

来源：

PEDIATRICS IN REVIEW | 2009年 / 30卷 / 06期

关键词：

SLEEP-ONSET INSOMNIA; EXOGENOUS MELATONIN; DOUBLE-BLIND; CHILDREN; DISORDERS; ADOLESCENTS; EFFICACY; SAFETY; ADHD;

D O I：

10.1542/pir.30-6-223

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Research suggests that melatonin appears to be efficacious in ameliorating SOL in both primary and secondary sleep disorders in children. Overall, melatonin appears to be safe in children who do not have contraindicated conditions or medications at doses between 0.5 and 7.5 mg before bedtime, with a low occurrence of mild adverse effects. Depending on the desired effect, parents and doctors should decide on the type of formulation to be used: long-term release (recommended for sustaining sleep) or short-term release (recommended for initiating sleep). Potential risk versus benefit of melatonin should be assessed on an individual basis, taking into account the child's health and concurrent medications. Copyright © 2009 by the American Academy of Pediatrics. All rights reserved.

引用

页码：223 / 228

页数：6

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