Vitamin D and Sjogren syndrome

被引：40

作者：

Garcia-Carrasco, Mario ^{[1
,2
]}

Alejandro Jimenez-Herrera, Erick ^{[1
]}

Luis Galvez-Romero, Jose ^{[3
]}

Vazquez de lara, Luis ^{[4
]}

Mendoza-Pinto, Claudia ^{[1
,2
]}

Etchegaray-Morales, Ivet ^{[1
]}

Munguia-Realpozo, Pamela ^{[5
]}

Ruiz-Arguelles, Alejandro ^{[6
,7
]}

Jose, Rosas ^{[8
]}

Vera-Recabarren, Mauricio ^{[9
]}

Cervera, Ricard ^{[10
]}

机构：

[1] Inst Mexicano Seguro Social, System Autoimmune Dis Res Unit, Gen Reg Hosp 36, Puebla, Mexico

[2] Benemerita Univ Autonoma Puebla, Med Sch, Dept Rheumatol & Immunol, Puebla, Mexico

[3] ISSSTE, Puebla Reg Hosp, Dept Inmunoallergol, Puebla, Mexico

[4] Benemerita Univ Autonoma Puebla, Med Sch, Dept Expt Med, Puebla, Mexico

[5] Inst Mexicano Seguro Social, Dept Rheumatol, Ctr Med Nacl La Raza, Puebla, Mexico

[6] Lab Clin Puebla, Puebla, Mexico

[7] Univ Americas Puebla, Cholula, Mexico

[8] Marina Baixa Hosp, Dept Rheumatol, Alicante, Spain

[9] Indisa Clin, Dept Dermatol, Santiago, Chile

[10] Hosp Clin Barcelona, Dept Autoimmune Dis, Barcelona, Catalonia, Spain

来源：

AUTOIMMUNITY REVIEWS | 2017年 / 16卷 / 06期

关键词：

Sjogren syndrome; Vitamin D; Immunomodulation; Environment; IMMUNE-SYSTEM; ULTRAVIOLET-RADIATION; 1,25-DIHYDROXYVITAMIN D-3; AUTOIMMUNE-DISEASES; RHEUMATIC-DISEASES; T-LYMPHOCYTES; RECEPTOR; LUPUS; CELLS; GENE;

D O I：

10.1016/j.autrev.2017.04.004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The immunomodulatory effects of vitamin D have been extensively studied in the context of autoimmunity. Multiple studies have demonstrated a high prevalence of vitamin D deficiency in autoimmune diseases. Recently, a possible protective role of vitamin D in autoimmunity has been described; however, this function remains controversial. Few studies have investigated the role of vitamin D in patients with Sjogren syndrome (SS). In this review, we compiled the main features of SS pathogenesis, the vitamin D immunomodulatory effects and the possible interaction between both. Data suggests that vitamin D may play a role in the SS pathogenesis. In addition, vitamin D low levels have been found in SS patients, which are associated with extra-glandular manifestations, such as lymphoma or neuropathy, suggesting a possible benefit effect of vitamin D in SS. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：587 / 593

页数：7

共 59 条

[1] Low levels of vitamin-D are associated with neuropathy and lymphoma among patients with Sjogren's syndrome [J].

Agmon-Levin, Nancy ;

Kivity, Shaye ;

Tzioufas, Athanasios G. ;

Lopez Hoyos, Marcus ;

Rozman, Blaz ;

Efes, Inga ;

Shapira, Yinon ;

Shamis, Ari ;

Amital, Howard ;

Youinou, Pierre ;

Shoenfeld, Yehuda .

JOURNAL OF AUTOIMMUNITY, 2012, 39 (03) :234-239

[2]

Albrecht J, 2006, CLIN EXP RHEUMATOL, V24, pS52

[3] GENETIC-CONTROL OF THE CD4/CD8 T-CELL RATIO IN HUMANS [J].

AMADORI, A ;

ZAMARCHI, R ;

DESILVESTRO, G ;

FORZA, G ;

CAVATTON, G ;

DANIELI, GA ;

CLEMENTI, M ;

CHIECOBIANCHI, L .

NATURE MEDICINE, 1995, 1 (12) :1279-1283

[4] Update on the immunobiology of Sjogren's syndrome [J].

Ambrosi, Aurelie ;

Wahren-Herlenius, Marie .

CURRENT OPINION IN RHEUMATOLOGY, 2015, 27 (05) :468-475

[5] Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern [J].

Ambrosi, Aurelie ;

Salomonsson, Stina ;

Eliasson, Hakan ;

Zeffer, Elisabeth ;

Skog, Amanda ;

Dzikaite, Vijole ;

Bergman, Gunnar ;

Fernlund, Eva ;

Tingstrom, Joanna ;

Theander, Elke ;

Rydberg, Annika ;

Skogh, Thomas ;

Ohman, Annika ;

Lundstrom, Ulla ;

Mellander, Mats ;

Winqvist, Ola ;

Fored, Michael ;

Ekbom, Anders ;

Alfredsson, Lars ;

Kallberg, Henrik ;

Olsson, Tomas ;

Gadler, Fredrik ;

Jonzon, Anders ;

Kockum, Ingrid ;

Sonesson, Sven-Erik ;

Wahren-Herlenius, Marie .

ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 (03) :334-340

[6] Vitamin D in "early" primary Sjogren's syndrome: does it play a role in influencing disease phenotypes? [J].

Baldini, Chiara ;

Delle Sedie, Andrea ;

Luciano, Nicoletta ;

Pepe, Pasquale ;

Ferro, Francesco ;

Talarico, Rosaria ;

Tani, Chiara ;

Mosca, Marta .

RHEUMATOLOGY INTERNATIONAL, 2014, 34 (08) :1159-1164

[7] SPECIFIC HIGH-AFFINITY RECEPTORS FOR 1,25-DIHYDROXYVITAMIN-D3 IN HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS - PRESENCE IN MONOCYTES AND INDUCTION IN LYMPHOCYTES-T FOLLOWING ACTIVATION [J].

BHALLA, AK ;

AMENTO, EP ;

CLEMENS, TL ;

HOLICK, MF ;

KRANE, SM .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1983, 57 (06) :1308-1310

[8] Evidence that vitamin D3 promotes mast cell-dependent reduction of chronic UVB-nduced skin pathology in mice [J].

Biggs, Lisa ;

Yu, Chunping ;

Fedoric, Boris ;

Lopez, Angel F. ;

Galli, Stephen J. ;

Grimbaldeston, Michele A. .

JOURNAL OF EXPERIMENTAL MEDICINE, 2010, 207 (03) :455-463

[9] Sjogren syndrome [J].

Brito-Zeron, Pilar ;

Baldini, Chiara ;

Bootsma, Hendrika ;

Bowman, Simon J. ;

Jonsson, Roland ;

Mariette, Xavier ;

Sivils, Kathy ;

Theander, Elke ;

Tzioufas, Athanasios ;

Ramos-Casals, Manuel .

NATURE REVIEWS DISEASE PRIMERS, 2016, 2

[10] Converging pathways lead to overproduction of IL-17 in the absence of vitamin D signaling [J].

Bruce, Danny ;

Yu, Sanhong ;

Ooi, Jot Hui ;

Cantorna, Margherita T. .

INTERNATIONAL IMMUNOLOGY, 2011, 23 (08) :519-528

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