Clinical Guidelines for the Management of Pouchitis

被引：88
作者：
Pardi, Darrell S. [1 ]
D'Haens, Geert [2 ]
Shen, Bo [3 ]
Campbell, Simon [4 ]
Gionchetti, Paolo [5 ]
机构：
[1] Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN USA
[2] Imelda GI Clin Res Ctr, Bonheiden, Belgium
[3] Cleveland Clin Fdn, Cleveland, OH 44195 USA
[4] Manchester Royal Infirm, Manchester M13 9WL, Lancs, England
[5] Univ Bologna, Bologna, Italy
来源：
INFLAMMATORY BOWEL DISEASES | 2009年 / 15卷 / 09期
关键词：
pouchitis; ileal pouch-anal anastomosis; ulcerative colitis; ANTINEUTROPHIL CYTOPLASMIC ANTIBODY; ULCERATIVE-COLITIS PATIENTS; INFLAMMATORY-BOWEL-DISEASE; ILEAL POUCH; RESTORATIVE PROCTOCOLECTOMY; ANAL ANASTOMOSIS; DOUBLE-BLIND; RISK-FACTORS; EXTRAINTESTINAL MANIFESTATIONS; REFRACTORY POUCHITIS;
D O I：
10.1002/ibd.21039
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
When surgery is necessary in patients with ulcerative colitis, total protocolectomy with ileal pouch-anal anastomosis (IPAA) is the procedure of choice. Several inflammatory and non-inflammatory complications can occur after IPAA. Pouchitis is the most common, occurring in approximate to 50% of patients. Whereas "acute" pouchitis can be treated rapidly and successfully in the majority of patients, "refractory" and "chronic pouchitis" remain therapeutic challenges to patients and physicians. This article reviews the literature and offers consensus guidelines on issues related to the epidemiology, diagnosis, pathogenesis, risk factors, and treatment of pouchitis.
引用
收藏
页码：1424 / 1431
页数：8
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