Trends in the Incidence of In-Hospital Mortality, Cardiogenic Shock, and Utilization of Mechanical Circulatory Support Devices in Myocarditis (Analysis of National Inpatient Sample Data, 2005-2014)

被引：43

作者：

Pahuja, Mohit ^{[1
]}

Adegbala, Oluwole ^{[2
]}

Mishra, Tushar ^{[3
]}

Akintoye, Emmanuel ^{[4
]}

Chehab, Omar ^{[3
]}

Mony, Shruti ^{[5
]}

Singh, Manmohan ^{[1
]}

Ando, Tomo ^{[1
]}

Abubaker, Hossam ^{[3
]}

Yassin, Ahmed ^{[3
]}

Subahi, Ahmed ^{[3
]}

Shokr, Mohamed ^{[1
]}

Ranka, Sagar ^{[6
]}

Briasoulis, Alexandros ^{[4
]}

Kapur, Navin K. ^{[7
]}

Burkhoff, Daniel ^{[8
,9
]}

Afonso, Luis ^{[1
]}

机构：

[1] Wayne State Univ, Detroit Med Ctr, Dept Inernal Med, Div Cardiol,Sch Med, 4201 St Antoine,Suite 5A, Detroit, MI 48201 USA

[2] Seton Hall Univ, Hackensack Meridian Sch Med, Engelwood Hosp & Med Ctr, Dept Internal Med, Engelwood, NJ USA

[3] Wayne State Univ, Detroit Med Ctr, Dept Inernal Med, Sch Med, Detroit, MI 48201 USA

[4] Univ Iowa, Coll Med, Dept Internal Med, Div Cardiol, Iowa City, IA 52242 USA

[5] Univ S Florida, Div Gastroenterol, Tampa, FL USA

[6] Cook Cty Hosp, Dept Internal Med, Chicago, IL 60612 USA

[7] Tufts Med Ctr, Dept Internal Med, Div Cardiol, Boston, MA 02111 USA

[8] Columbia Univ, Cardiovasc Res Fdn, Med Ctr, New York, NY USA

[9] Columbia Univ, Div Cardiol, Med Ctr, Dept Internal Med, New York, NY USA

来源：

JOURNAL OF CARDIAC FAILURE | 2019年 / 25卷 / 06期

关键词：

Myocarditis; cardiogenic shock; mechanical circulatory support devices; EXTRACORPOREAL MEMBRANE-OXYGENATION; ACUTE FULMINANT MYOCARDITIS; VENTRICULAR ASSIST DEVICE; ENDOMYOCARDIAL BIOPSY; EUROPEAN-SOCIETY; DILATED CARDIOMYOPATHY; HEART-FAILURE; TASK-FORCE; ASSOCIATION; CARDIOLOGY;

D O I：

10.1016/j.cardfail.2019.04.012

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Myocarditis may be associated with hemodynamic instability and portends a poor prognosis when associated with cardiogenic shock (CS). There are limited data available on the incidence of in-hospital mortality, CS, and utilization of mechanical circulatory support (MCS) devices in these patients. Methods: We queried the 2005-2014 National Inpatient Sample databases to identify all patients aged >18 years with myocarditis in the United States. Results: The number of reported cases of myocarditis per 1 million gradually increased from 95 in 2005 to 144 in 2014 (Pfor trend < .01). The trend and incidence of endomyocardial biopsy remained the same despite the increase in clinical diagnosis. Overall, in-hospital mortality was 4.43% of total admissions without a change in overall trend over the study period. We also observed a significant increase in the incidence of CS from 6.94% in 2005 to 11.99% in 2014 (Pfor trend < .01). There was a parallel increase in the utilization of advanced MCS devices during the same time period such as extracorporeal membrane oxygenation or percutaneous cardiopulmonary support (0.32% in 2005 to 2.1% in 2014; P < .01) and percutaneous ventricular assist devices such as ImpellaJtandem heart (0.176% in 2005 to 1.75% in 2014; P < .01). Conclusion: Although the incidence of myocarditis has increased in the last decade, the in-hospital mortality has remained the same despite increases in the incidence of CS, possibly reflecting the benefits of increased usage of advanced MCS devices. We noted that increasing age, presence of multiple comorbidities and CS were associated with an increase in in-patient mortality.

引用

页码：457 / 467

页数：11