Do antipsychotic drugs shrink the brain? Probably not

被引:3
作者
Lawrie, Stephen M. [1 ]
机构
[1] Univ Edinburgh, Royal Edinburgh Hosp, Div Psychiat, Edinburgh EH10 5HF, Midlothian, Scotland
关键词
SCHIZOPHRENIA; METAANALYSIS;
D O I
10.1177/02698811221092252
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:425 / 427
页数:3
相关论文
共 12 条
[1]   Differentiating the effect of antipsychotic medication and illness on brain volume reductions in first-episode psychosis: A Longitudinal, Randomised, Triple-blind, Placebo-controlled MRI Study [J].
Chopra, Sidhant ;
Fornito, Alex ;
Francey, Shona M. ;
O'Donoghue, Brian ;
Cropley, Vanessa ;
Nelson, Barnaby ;
Graham, Jessica ;
Baldwin, Lara ;
Tahtalian, Steven ;
Yuen, Hok Pan ;
Allott, Kelly ;
Alvarez-Jimenez, Mario ;
Harrigan, Susy ;
Sabaroedin, Kristina ;
Pantelis, Christos ;
Wood, Stephen J. ;
McGorry, Patrick .
NEUROPSYCHOPHARMACOLOGY, 2021, 46 (08) :1494-1501
[2]   Effect of antipsychotic drugs on brain morphometry. A randomized controlled one-year follow-up study of haloperidol, risperidone and olanzapine [J].
Crespo-Facorro, Benedicto ;
Roiz-Santianez, Roberto ;
Perez-Iglesias, Rocio ;
Pelayo-Teran, Jose M. ;
Rodriguez-Sanchez, Jose M. ;
Tordesillas-Gutierrez, Diana ;
Ramirez, MariLuz ;
Martinez, Obdulia ;
Gutierrez, Agustin ;
de Lucas, Enrique Marco ;
Vazquez-Barquero, Jose L. .
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2008, 32 (08) :1936-1943
[3]  
Fountoulakis K., 2022, J PSYCHOPHARMACOL, V36, P428
[4]   Cerebral cortical gray expansion associated with two second-generation antipsychotics [J].
Garver, DL ;
Holcomb, JA ;
Christensen, JD .
BIOLOGICAL PSYCHIATRY, 2005, 58 (01) :62-66
[5]   Brain abnormality in schizophrenia - A systematic and quantitative review of volumetric magnetic resonance imaging studies [J].
Lawrie, SM ;
Abukmeil, SS .
BRITISH JOURNAL OF PSYCHIATRY, 1998, 172 :110-120
[6]   Are structural brain changes in schizophrenia related to antipsychotic medication? A narrative review of the evidence from a clinical perspective [J].
Lawrie, Stephen M. .
THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY, 2018, 8 (11) :319-326
[7]   Antipsychotic drug effects on brain morphology in first-episode psychosis [J].
Lieberman, JA ;
Tollefson, GD ;
Charles, C ;
Zipursky, R ;
Sharma, TN ;
Kahn, RS ;
Keefe, RSE ;
Green, AI ;
Gur, RE ;
McEvoy, J ;
Perkins, D ;
Hamer, RM ;
Gu, HB ;
Tohen, M .
ARCHIVES OF GENERAL PSYCHIATRY, 2005, 62 (04) :361-370
[8]   Are There Progressive Brain Changes in Schizophrenia? A Meta-Analysis of Structural Magnetic Resonance Imaging Studies [J].
Olabi, Bayanne ;
Ellison-Wright, Ian ;
McIntosh, Andrew M. ;
Wood, Stephen J. ;
Bullmore, Edward T. ;
Lawrie, Stephen M. .
BIOLOGICAL PSYCHIATRY, 2011, 70 (01) :88-96
[9]   Hippocampal volume and hippocampal neuron density, number and size in schizophrenia: a systematic review and meta-analysis of postmortem studies [J].
Roeske, Maxwell J. ;
Konradi, Christine ;
Heckers, Stephan ;
Lewis, Alan S. .
MOLECULAR PSYCHIATRY, 2021, 26 (07) :3524-3535
[10]   The Neuro/PsyGRID Calibration Experiment: Identifying Sources of Variance and Bias in Multicenter MRI Studies [J].
Suckling, John ;
Barnes, Anna ;
Job, Dominic ;
Brennan, David ;
Lymer, Katherine ;
Dazzan, Paola ;
Marques, Tiago Reis ;
MacKay, Clare ;
McKie, Shane ;
Williams, Steve R. ;
Williams, Steven C. R. ;
Deakin, Bill ;
Lawrie, Stephen .
HUMAN BRAIN MAPPING, 2012, 33 (02) :373-386