Application of Zwitterionic Polymers in the Treatment of Malignant Tumors

被引:7
|
作者
Chen Jie [1 ]
Li Xiaozhou [1 ,2 ]
Tian Huayu [1 ]
Zhu Xiaojuan [2 ]
Chen Xuesi [1 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, Key Lab Polymer Ecomat, Changchun 130022, Peoples R China
[2] NE Normal Univ, Minist Educ, Inst Cytol & Genet, Key Lab Mol Epigenet, Changchun 130024, Peoples R China
来源
基金
中国国家自然科学基金;
关键词
Zwitterionic polymer; Drug delivery; Gene delivery; Medical diagnosis; Antitumor; IN-VITRO; SHIELDING SYSTEM; ANTITUMOR DRUG; DELIVERY; GENE; CHARGE; NANOPARTICLES; SIRNA; DOXORUBICIN; DIAGNOSIS;
D O I
10.7503/cjcu20150608
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Zwitterionic polymer is a kind of polymer both with acidic and basic groups, which exists in the form of zwitterion. Zwitterionic polymers have attracted our widespread attention because of the excellent performance of themselves, such as high hydration ability, significant anti-bacterial adhesion ability, charge conversion, be easily modified and so on. In this review, the variety of zwitterionic polymers will be classified according to the structure. The early diagnosis and treatment of malignant tumors by zwitterionic polymers were analyzed and summarized in this paper. Finally, the development of zwitterionic polymers in future is prospected.
引用
收藏
页码:2148 / +
页数:9
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