Induction of glutathione S-transferase activity in Triatoma infestans

被引：34
|
作者：
Sivori, JL
Casabe, N
Zerba, EN
Wood, EJ
机构：
[1] UNIV BUENOS AIRES,FAC CIENCIAS EXACTAS & NAT,RA-1053 BUENOS AIRES,DF,ARGENTINA
[2] CONSEJO NACL INVEST CIENT & TECN,CITEFA,CIPEIN,CTR INVEST PLAGAS & INSECTICIDAS,BUENOS AIRES,DF,ARGENTINA
来源：
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 1997年 / 92卷 / 06期
关键词：
Triatoma infestans; glutathione S-transferase; induction;
D O I：
10.1590/S0074-02761997000600013
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Several synthetic pesticides and allelochemicals used to treat Triatoma infestans adults by topic application showed some degree of cytosolic glutathione S-transferase (GST) induction. General inducers of detoxication systems such as phenobarbital and 3-methylcholantrene topically applied on T. infestans resulted in no GST induction. Meanwhile, general insecticide synergist such as piperonyl butoxide (160 mu g/insect) increased the GST-activity in the range of 120-140%. Insects injected with reduced glutathione (300 mg/insect) presented at the forth day elevated GST activity.
引用
收藏
页码：797 / 802
页数：6
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