A colorimetric and near-infrared fluorescent probe for cysteine and homocysteine detection

被引：24

作者：

Yang, Xiaojing ^{[1
]}

Wang, Yingying ^{[1
]}

Zhao, Mei-xia ^{[1
]}

Yang, Wei ^{[2
]}

机构：

[1] Henan Univ, Key Lab Nat Med & Immune Engn Henan Prov, Kaifeng 475004, Peoples R China

[2] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2019年 / 212卷

关键词：

Cysteine; NIR fluorescence; Colorimetric; SELECTIVE DETECTION; HYDROGEN-SULFIDE; GLUTATHIONE; GSH; MITOCHONDRIA; APOPTOSIS; CYS;

D O I：

10.1016/j.saa.2018.12.042

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

By introducing the S-aryl substituents at the central carbon on heptamethine cyanine, we have developed a near-infrared fluorescent probe Cy.7-PT. The probe had the high selectivity for the colorimetric detection of Cys/Hcy with the color changing from light green to blue. Cys could be quantitatively detected and the detection limit is 0.39 mu M. Cell imaging and spiked samples experiments prove that the probe Cy.7-PT is suitable for monitoring and visualizing Cys in vitro and living cells. (C) 2018 Published by Elsevier B.V.

引用

页码：10 / 14

页数：5

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