A successful Treatment of Buprenorphine Withdrawal with the Dopamine Receptor Agonist Pramipexole

被引：5
作者：
Makhinson, Michael [1 ,2 ]
Gomez-Makhinson, Juliana [1 ,2 ]
机构：
[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90095 USA
[2] Harbor UCLA Med Ctr, Dept Psychiat, Torrance, CA 90509 USA
来源：
AMERICAN JOURNAL ON ADDICTIONS | 2014年 / 23卷 / 05期
关键词：
OPIATE WITHDRAWAL; OPIOID WITHDRAWAL; NUCLEUS-ACCUMBENS; MANAGEMENT; SYMPTOMS;
D O I：
10.1111/j.1521-0391.2014.12133.x
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
Background: Buprenorphine, used for treating opioid dependence, may have a withdrawal syndrome requiring treatment. Modulation of the dopamine system, which has been implicated in opioid withdrawal, may be a target for withdrawal for opioids such as buprenorphine. Case Report: A case is reported of a buprenorphine withdrawal syndrome with predominant symptoms of restlessness that were resistant to clonidine and benzodiazepines. It was successfully treated with the dopamine agonist pramipexole. Scientific Significance: Dopamine receptor agonists may have a place in the treatment of restlessness associated with opioid withdrawal and may have value for the broader spectrum of opioid withdrawal symptoms.
引用
收藏
页码：475 / 477
页数：3
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