Effects of Cinnamomum Zeylanicum Treatment on Radiolabeling of Blood Constituents and Morphology of Red Blood Cells in Wistar Rats

被引:5
|
作者
Benarroz, Monica Oliveira [1 ]
Rocha, Gabrielle de Souza [2 ]
Pereira, Marcia Oliveira [2 ]
Geller, Mauro
da Fonseca, Adenilson de Souza [1 ,3 ]
Presta, Giuseppe Antonio [4 ]
Bernardo-Filho, Mario [1 ]
机构
[1] Univ Fed Rio de Janeiro, Inst Biol Roberto Alcantara Gomes, Dept Biofis & Biometria, BR-20551030 Rio De Janeiro, Brazil
[2] Univ Fed Rio Grande do Norte, BR-59010180 Natal, RN, Brazil
[3] Ctr Univ Serra Orgaos, Ctr Ciencias Saude, BR-25964004 Teresopolis, RJ, Brazil
[4] Univ Fed Estado Rio de Janeiro, Inst Biomed, Dept Fisiol Humana, BR-20211040 Rio De Janeiro, Brazil
关键词
blood constituents; Cinnamomum zeylanicum; technetium-99m;
D O I
10.1590/S1516-89132008000700023
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The aim of this study was to evaluate the effect of in vivo treatment with an aqueous cinnamon extract on the labeling of blood constituents with Tc-99m and on the morphology of red blood cells from Wistar rats. Animals were treated with cinnamon extract at different doses and for different periods of time. As controls, animals treated with 0.9% NaCl. Labeling of blood constituents with Tc-99m was performed. Plasma, blood cells and insoluble fractions were isolated. Radioactivity in each fraction was counted and the percentage of radioactivity (%ATI) was calculated. Also, blood smears were prepared to morphological analysis of red blood cells from. Data showed that in vivo cinnamon extract did not significantly (p>0.05) modify the %ATI of blood constituents and morphology of red blood cells. The results suggest that in vivo aqueous cinnamon could not affect the membrane structures involved in transport of ions or the oxidation state of stannous and pertechnetate ions.
引用
收藏
页码:143 / 149
页数:7
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