Degradation of forensic DNA profiles

被引：52

作者：

Bright, Jo-Anne ^{[1
,2
]}

Taylor, Duncan ^{[3
]}

Curran, James M. ^{[2
]}

Buckleton, John S. ^{[1
]}

机构：

[1] ESR, Auckland 1025, New Zealand

[2] Univ Auckland, Dept Stat, Auckland 1025, New Zealand

[3] Forens Sci South Australia, Adelaide, SA 5000, Australia

来源：

AUSTRALIAN JOURNAL OF FORENSIC SCIENCES | 2013年 / 45卷 / 04期

关键词：

forensic DNA; PowerPlex; 21; degradation; AMPLIFICATION; SAMPLES;

D O I：

10.1080/00450618.2013.772235

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Selected profiles typed at the Promega PowerPlex 21 (PP21) loci were examined to determine if a linear or exponential model best described the relationship between peak height and molecular weight. There were fewer large departures from observed and expected peak heights using the exponential model. The larger differences that were observed were exclusively at the high molecular weight loci. We conclude that the data supports the use of an exponential curve to model peak heights versus molecular weight in PP21 profiles. We believe this observation will improve our ability to model expected peak heights for use in DNA interpretation software.

引用

页码：445 / 449

页数：5

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